Results 41 to 50 of about 7,288 (241)

TLR3 promotes MMP-9 production in primary human airway epithelial cells through Wnt/β-catenin signaling

Respiratory Research, 2017
Background Airway epithelial cells (AEC) act as the first line of defence in case of lung infections. They constitute a physical barrier against pathogens and they participate in the initiation of the immune response.
P.-J. Royer, K. Henrio, M. Pain, J. Loy, A. Roux, A. Tissot, P. Lacoste, C. Pison, S. Brouard, A. Magnan, the COLT consortium   +10 more
doaj   +1 more source

Mucoviscidose : les techniques instrumentales de désencombrement des voies aériennes [PDF]

, 2012
Introduction : Le recours aux manœuvres de désencombrement des voies aériennes fait partie intégrante de la prise en charge de la mucoviscidose. De nombreuses techniques sont décrites sans qu’une unanimité existe.
Reychler, Gregory, Leonard, Anissa, A. Leonard, Lebecque, Patrick, P. Lebecque, G. Reychler, A. Palem, T. Coppens, Coppens, Thibault, Palem, Alain   +9 more
core   +1 more source

The Prognosis of ART Is Not Altered in Cystic Fibrosis Women: A Case-Report Study

Frontiers in Endocrinology, 2022
Research QuestionUnlike in men, a very limited number of studies were focused on the specificity of ART management of cystic fibrosis (CF) in women. The purpose of this study was to determine the causes of infertility in patients, the appropriate ART ...
Inès Braham, Adeline Morisot, Samir Boukaïdi, Marie Perceval, Isabelle Durieu, Christine Rousset-Jablonski, Sylvie Hieronimus, Sylvie Leroy, Nicolas Chevalier, Nicolas Chevalier   +9 more
doaj   +1 more source

Neonatal low respiratory tract chlamydia trachomatis infection: Diagnostic and treatment management

Respiratory Medicine Case Reports, 2019
Maternal infection during pregnancy by Chlamydia trachomatis (Chlamydia t.) can result in neonatal interstitial lung disease. It remains difficult for physicians to establish this diagnosis and to select the best treatment, as there is no recommendation.
M. Jouglet, I. Wuillaume, C. Buchs, P. Reix, C. Schweitzer, L. Coutier   +5 more
doaj   +1 more source

The gut-lung axis in the CFTR modulator era

Frontiers in Cellular and Infection Microbiology, 2023
The advent of CFTR modulators represents a turning point in the history of cystic fibrosis (CF) management, changing profoundly the disease’s clinical course by improving mucosal hydration.
Florian Lussac-Sorton, Florian Lussac-Sorton, Éléna Charpentier, Éléna Charpentier, Sébastien Imbert, Sébastien Imbert, Sébastien Imbert, Maxime Lefranc, Stéphanie Bui, Stéphanie Bui, Stéphanie Bui, Michael Fayon, Michael Fayon, Michael Fayon, Patrick Berger, Patrick Berger, Patrick Berger, Raphaël Enaud, Raphaël Enaud, Raphaël Enaud, Laurence Delhaes, Laurence Delhaes, Laurence Delhaes   +22 more
doaj   +1 more source

Prévalence de Pneumocystis jirovecii chez les patients atteints de mucoviscidose en Bretagne [PDF]

, 2015
National audiencePneumocystis jirovecii (P. jirovecii) est un champignon atypique et transmissible à fort tropisme pulmonaire. La prévalence de P. jirovecii chez les patients atteints de mucoviscidose a été évaluée en Allemagne à 7,4 %, en Espagne à 21,6 
Le Gal, Solène, Damiani, Céline, Deneuville, Eric, Robert-Gangneux, Florence, Totet, Anne, Ramel, Sophie, Nevez, Gilles, Virmaux, Michele, Belleguic, Chantal, Rault, Gilles, Gangneux, Jean-Pierre   +10 more
core   +1 more source

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

British Journal of Clinical Pharmacology, EarlyView.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo, Venceslas Bourdin, Abd El Kader Ait Tayeb, Sihem Benaboud, Inès Martins, Caroline Joyau, Myriam Benhamida, Isabelle Sermet‐Gaudelus, Clémence Martin, Pierre Régis Burgel, Céline Verstuyft, Laurent Chouchana, Estelle Ayme‐Dietrich   +12 more
wiley   +1 more source

Les origines de la mucoviscidose [PDF]

, 2021
Les origines de la mucoviscidose en Bretagne ont déjà été abordées par André Chaventré, Ingrid Duguépéroux et Marc de Braekeleer pour trois mutations. L’originalité de ce travail résulte dans la quantité et la profondeur des généalogies collectées.
Pellen, Nadine
core   +1 more source

Long term NIV in an infant with Hallermann-Streiff syndrome: A case report and overview of respiratory morbidity

Frontiers in Pediatrics, 2022
Hallermann-Streiff syndrome (HSS) is a rare congenital syndrome with different anomalies including midface hypoplasia, beak nose and micrognathia. The upper airways narrowness can lead to severe respiratory complications such as obstructive sleep apnoea ...
S Guerin, S Blanchon, Q de Halleux, V Bayon, T Ferry   +4 more
doaj   +1 more source

Prenatal CFTR modulator therapy for fetal cystic fibrosis: Emerging evidence, clinical considerations, and future directions

Pregnancy, Volume 2, Issue 4, July 2026.
Abstract Background The consequences of cystic fibrosis (CF) transmembrane conductance regulator (CFTR) protein dysfunction or absence begin during fetal development, with pancreatic, intestinal, hepatobiliary, and reproductive manifestations evident at birth.
Hiba J. Mustafa, Yair J. Blumenfeld, Ramen H. Chmait, Jennifer L. Taylor‐Cousar, Jordana E. Hoppe, Stacey L. Martiniano, Angela Metcalf, Scott D. Sagel, Edith T. Zemanick, Alireza A. Shamshirsaz, Sylvia E. Szentpetery, Aaron T. Trimble, Elizabeth B. Burgener, Carmen Luna‐Paredes, Isabelle Sermet‐Gaudelus, Michael V. Zaretsky   +15 more
wiley   +1 more source