Results 41 to 50 of about 1,531 (166)

A intersubjetividade no contexto da família de pessoas com fibrose cística

Revista Brasileira de Enfermagem, 2012
Trata-se de uma investigação qualitativa, com aproximação fenomenológica, que objetivou desvelar os processos intersubjetivos no contexto da família de pessoas com Fibrose Cística (FC).
Geisa Santos Luz, Silvana Sidney Costa Santos, Valéria Lerch Lunardi, Ellen Dayane Cargnin Pimentel, Sandra Marisa Pelloso, Maria Dalva de Barros Carvalho   +5 more
doaj   +1 more source

Implementation of Model-Based Dose Adjustment of Tobramycin in Adult Patients with Cystic Fibrosis

Pharmaceutics, 2022
Therapeutic drug monitoring (TDM) of tobramycin is widely performed in patients with cystic fibrosis (CF), but little is known about the value of model-informed precision dosing (MIPD) in this setting.
Jérémy Reverchon, Vianney Tuloup, Romain Garreau, Viviane Nave, Sabine Cohen, Philippe Reix, Stéphane Durupt, Raphaele Nove-Josserand, Isabelle Durieu, Quitterie Reynaud, Laurent Bourguignon, Sandrine Charles, Sylvain Goutelle   +12 more
doaj   +1 more source

Prática fisioterapêutica no tratamento da fibrose cística

ABCS Health Sciences, 2014
A fibrose cística (FC), denominada também de mucoviscidose, é uma doença genética do tipo autossômica recessiva que acomete principalmente crianças e indivíduos de raça branca.
Carolina Lazzarim de Conto, Cintia Teixeira Vieira, Kelen Nunes Fernandes, Laís Machado Jorge, Gabriela da Silva Cândido, Rafael Inácio Barbosa, Rafael Cypriano Dutra   +6 more
doaj   +1 more source

Assessment of the efficacy of an antimicrobial peptide in the context of cystic fibrosis airways

Current Research in Microbial Sciences
Antimicrobial peptides (AMPs) offer a promising alternative to control airway infections with multi-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), which commonly infects patients with cystic fibrosis (CF).
Albane Jouault, Inès Jeguirim, Inès Ben Hadj Kaddour, Lhousseine Touqui   +3 more
doaj   +1 more source

Proteomic profiling of sweat in patients with cystic fibrosis provides new insights into epidermal homoeostasis

Skin Health and Disease, 2023
Background A high proportion of patients with Cystic Fibrosis (CF) also present the rare skin disease aquagenic palmoplantar keratoderma. A possible link between this condition and absence of a functional CF Transmembrane conductance Regulator protein in
Matthieu Cornet, Thao Nguyen‐Khoa, Mairead Kelly‐Aubert, Vincent Jung, Frédérique Chedevergne, Muriel Le Bourgeois, Laura Aoust, Kévin Roger, Chiara Ida Guerrera, Isabelle Sermet‐Gaudelus   +9 more
doaj   +1 more source

Phenotype‐Genotype Correlations in ABCA3 Patients—The RespiRare Cohort

Pediatric Pulmonology, Volume 60, Issue 10, October 2025.
ABSTRACT Background ATP‐binding cassette transporter A3 (ABCA3) deficiency is one of the most severe causes of childhood interstitial lung diseases (chILD). This study aims to report the RespiRare ABCA3 cohort and to establish phenotype‐genotype correlations. Methods Phenotypic and genotypic data of patients under 18 years were retrospectively included
Manon Fleury, Céline Delestrain, Alice Hadchouel, Julie Mazenq, Myriam Benhamida, Anne‐Sophie Bernard, Raphaël Borie, Jacques Brouard, Harriet Corvol, Pierrick Cros, Christophe Delacourt, Tifenn Desroziers, Jean‐Christophe Dubus, Carole Egron, Ralph Epaud, Michael Fayon, Aude Forgeron, Lisa Giovannini‐Chami, Christophe Marguet, Alexandra Masson‐Rouchaud, Hortense Petat, Marie‐Catherine Renoux, Léa Roditis, Caroline Thumerelle, Clémentine Vigier, Aurore Coulomb L'Herminé, Hubert Ducou le Pointe, Pascale Fanen, Camille Fletcher, Chiara Sileo, Laureline Berteloot, Camille Louvrier, Alix de Becdelièvre, Marie Legendre, Nadia Nathan   +34 more
wiley   +1 more source

A Importância das Associações de Fibrose Cística na Vida dos Pacientes e Familiares

Clinical and Biomedical Research, 2011
Na organização da sociedade moderna as associações filantrópicas tornaram-se importantes no cenário mundial.No Brasil após a fundação da ABRAM várias associações regionais se estruturaram para defender os pacientes com Fibrose Cística.No RGS, duas ...
Cleci Furian Müller, Elizabete Backes
doaj  

One year of ETI reduces lung bacterial colonisation in adults with cystic fibrosis

Scientific Reports
The triple combination elexacaftor-tezacaftor-ivacaftor (ETI) has provided unprecedented clinical benefits for people with cystic fibrosis (pwCF) and drastically transformed the outcome of this disease.
Lucile Mianowski, Anne Doléans-Jordheim, Laurent Barraud, Muriel Rabilloud, Mael Richard, Raphaele Nove Josserand, Isabelle Durieu, Quitterie Reynaud   +7 more
doaj   +1 more source

Expression and Roles of Antimicrobial Peptides in Innate Defense of Airway Mucosa: Potential Implication in Cystic Fibrosis

Frontiers in Immunology, 2020
The treatment of respiratory infections is associated with the dissemination of antibiotic resistance in the community and clinical settings. Development of new antibiotics is notoriously costly and slow; therefore, alternative strategies are needed ...
Regina Geitani, Carole Ayoub Moubareck, Carole Ayoub Moubareck, Zhengzhong Xu, Zhengzhong Xu, Zhengzhong Xu, Dolla Karam Sarkis, Lhousseine Touqui, Lhousseine Touqui   +8 more
doaj   +1 more source

Isoniazid‐Dihydropyrimidinone Molecular Hybrids: Design, Synthesis, Antitubercular Activity, and Cytotoxicity Investigations with Computational Validation

ChemMedChem, Volume 20, Issue 11, June 2, 2025.
Antitubercular evaluation of a novel library of isoniazid‐dihydropyrimidinone molecular hybrids (8a–8n) discloses a potent compound with MIC = 0.39μg mL−1 against M. tuberculosis mc26230. Cytotoxicity, stability, and in silico studies, including molecular docking and ADME/T (absorption, distribution, metabolism, excretion, and toxicity) analysis ...
Gobind Kumar, Pule Seboletswe, Sahil Mishra, Neha Manhas, Safiyah Ghumran, Nagaraju Kerru, Françoise Roquet‐Banères, Maëlle Foubert, Laurent Kremer, Gaurav Bhargava, Parvesh Singh   +10 more
wiley   +1 more source