Results 81 to 90 of about 5,413 (194)

BSV163/DOPE‐mediated TRAIL gene transfection acts synergistically with chemotherapy against cisplatin‐resistant ovarian cancer

Chemical Biology &Drug Design, Volume 103, Issue 1, January 2024.
Ovarian cancer is the most lethal gynecologic cancer with recurrent or resistant disease observed in 70% of patients. We described herein the anti‐cancer effect of a novel lipid vector BSV163/DOPE‐mediated TRAIL gene transfection in association with cisplatin in—sensitive and—resistant ovarian cancer cells.
Quoc Manh Nguyen, Pierre‐François Dupré, Mathieu Berchel, Rosy Ghanem, Paul‐Alain Jaffrès, Frédérique d'Arbonneau, Tristan Montier   +6 more
wiley   +1 more source

Etude du profil d'activation des macrophages alvéolaires chez le transplanté pulmonaire [PDF]

, 2015
La transplantation pulmonaire est une option thérapeutique d'ultime recours pour les patients souffrant de maladies pulmonaires telles que la broncho-pneumopathie chronique obstructive (BPCO), la mucoviscidose, l'hypertension artérielle pulmonaire se ...
WAELCHLI, S.
core  

Comorbidités et risques de décès après transplantation pulmonaire [PDF]

, 2015
Contexte: Bien que la transplantation pulmonaire offre un avantage de survie conséquent, l'intervention chirurgicale et le traitement immunosuppresseur modifient le profil des comorbidités.
BILAT, O.
core  

L'école à l'hôpital: quelle scolarité pour les enfants malades [PDF]

, 2014
Ce travail de recherche traite de la scolarité des enfants malades et de l’école à l’hôpital. Je me suis intéressée à la vie de ces enfants, une fois qu’ils n’ont plus la possibilité de rester en classe régulière et à ce qui est mis en place pour leur ...
Sperandio, Lorane, Voélin-Chatelain, Nicole   +1 more
core  

CSN5 binds to misfolded CFTR and promotes its degradation [PDF]

, 2008
Cystic fibrosis is mainly caused by mutations that interfere with the biosynthetic folding of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The aim of this study was to find cellular proteins interacting with CFTR and regulating
Tanguy, Gaëlle, Drévillon, Loïc, Arous, Nicole, Hasnain, Afia, Hinzpeter, Alexandre, Fritsch, Janine, Goossens, Michel, Fanen, Pascale   +7 more
core   +1 more source

Lipoxin A4 and interleukin-8 levels in cystic fibrosis sputum after antibiotherapy [PDF]

, 2008
Antibiotics are largely prescribed for cystic fibrosis (CF) respiratory exacerbations. Effects of antibiotics on the inflammatory profile of the patients have been shown but remain controversial.
Belluomini, L., Bordi, P., Chella, A., Danesi, R., Del Re, M., Di Costanzo, F. D., Falcone, A., Frassoldati, A., Mazzoni, F., Morganti, R., Petrini, I., Restante, G., Rofi, E., Steendam, C. M. J., Tiseo, M., van Schaik, R. H. N., Vasile, E.   +16 more
core   +4 more sources

Aberrant Splicing Is the Pathogenicity Mechanism of the p.Glu314Lys Variant in CYP11A1 Gene

Frontiers in Endocrinology, 2018
Context: The cholesterol side chain cleavage enzyme (CYP11A1) catalyzes the conversion of cholesterol to pregnenolone, the first rate-limiting step of steroidogenesis.
Claire Goursaud, Delphine Mallet, Delphine Mallet, Alexandre Janin, Alexandre Janin, Alexandre Janin, Rita Menassa, Rita Menassa, Véronique Tardy-Guidollet, Véronique Tardy-Guidollet, Véronique Tardy-Guidollet, Gianni Russo, Anne Lienhardt-Roussie, Claudine Lecointre, Ingrid Plotton, Ingrid Plotton, Ingrid Plotton, Yves Morel, Yves Morel, Yves Morel, Florence Roucher-Boulez, Florence Roucher-Boulez, Florence Roucher-Boulez   +22 more
doaj   +1 more source

Cationic antimicrobial peptides: alternatives and/or adjuvants to antibiotics active against methicillin-resistant Staphylococcus aureus and multidrug-resistant Pseudomonas aeruginosa

BMC Microbiology, 2019
Background Methicillin-resistant Staphylococcus aureus and multidrug-resistant Pseudomonas aeruginosa are becoming difficult to treat with antibiotics whereas Cationic Antimicrobial Peptides (CAMPs) represent promising alternatives.
Regina Geitani, Carole Ayoub Moubareck, Lhousseine Touqui, Dolla Karam Sarkis   +3 more
doaj   +1 more source

Surfactant protein a in cystic fibrosis: supratrimeric structure and pulmonary outcome. [PDF]

, 2012
The state of oligomerization of surfactant associated protein-A (SP-A) monomers differs between individuals. This likely affects SP-A's functional properties and could thereby influence clinical status in patients with lung diseases.
Ballmann, Manfred, Griese, Matthias, Heinrich, Stephanie, Kabesch, Michael, Kappler, Matthias, Paul, Karl, Ratjen, Felix, Rietschel, Ernst   +7 more
core   +2 more sources

Fibrose Cística: Diagnóstico e Tratamento

Clinical and Biomedical Research, 2011
Fibrose Cística, também chamada de mucoviscidose, é uma doença crônica, de origem genética, causada por um gene defeituoso herdado do pai e outro da mãe. Não é, portanto, uma doença contagiosa.
Anneliese Hoffmann
doaj