Normal mucus formation requires cAMP-dependent HCO3- secretion and Ca2+-mediated mucin exocytosis. [PDF]
Evidence from the pathology in cystic fibrosis (CF) and recent results in vitro indicate that HCO3- is required for gel-forming mucins to form the mucus that protects epithelial surfaces.
Garcia, Mary Abigail S +2 more
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Treatment adherence in individuals with cystic fibrosis: An Observational Study
Introduction: Low treatment adherence is a complex issue frequently observed in cystic fibrosis (CF) patients. Objective: To evaluate the self-reported treatment adherence rate and the rate determined based on pharmacy medication dispensation records in
Fernanda Fontelle +5 more
doaj +1 more source
Acceso venoso central mediante cápsulas de inyección subcutáneas. Serie de 124 dispositivos [PDF]
Presentamos una serie de 111 pacientes (límites: 9 meses - 78 años) en los que se colocaron 124 dispositivos como modalidad de acceso venoso central. Se analizan las complicaciones aparecidas durante su utilización, que actualmente sobrepasa los 1.100 ...
Albiach, M. (M.) +7 more
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Aim. Study the spectrum of resistance to antibiotics and its variability of Staphylococcus aureus, Pseudomonas aeruginosa and Вurkholderia cepacia complex (BCC), persisting in lungs of MV patients. Materials and methods. 312 strains of S.
L. R Avetisyan +10 more
doaj
Use of inhaled tobramycin in patients with cystic fibrosis
The results of a few studies evaluating the efficacy and safety of nebulized tobramycin solution used in patients with cystic fibrosis have been published to date. Pulmonary deposition of inhaled tobramycin and its lung produced concentrations are rather
A G Chermensky, M E Gembitskaya
doaj
IMMUNE PREVENTION OF RESPIRATORY-SYNCYTIAL VIRAL INFECTION: 15 YEARS OF WORLD EXPERIENCE
The article is dedicated to one of the most important issues of modern neonatology – prevention of respiratory-syncytial virus infection, which is a frequent cause of bronchiolites and pneumoniae in infants and neonates, especially premature infants. The
E. S. Keshishyan
doaj +1 more source
Ubiquitin C-terminal hydrolase L1 (UCH-L1):Structure, distribution and roles in brain function and dysfunction [PDF]
Ubiquitin C-terminal hydrolase L1 (UCH-L1) is an extremely abundant protein in the brain where, remarkably, it is estimated to make up 1–5% of total neuronal protein.
Bishop, Paul, Henley, Jeremy, Rocca, Dan
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Cystic Fibrosis Atypical Forms Presentation: Edema, Anemia and Skin Lesions
Cystic fibrosis or mucoviscidosis is the most common genetic disease in the Caucasian race characterized by thickening of secretions due to abnormal ion transport of epithelial cells, manifested with pancreatic insufficiency, progressive lung disease ...
Chabelys de la Caridad Rodríguez Membrides +2 more
doaj +2 more sources
Expanded carrier screening: A current perspective [PDF]
Prenatal carrier screening has expanded to include a large number of genes offered to all couples considering pregnancy or with an ongoing pregnancy.
Al-Kouatly, Hb +12 more
core +1 more source
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis [PDF]
Background: People with cystic fibrosis, who are chronically colonised with the organism Pseudomonas aeruginosa, often require multiple courses of intravenous aminoglycoside antibiotics for the management of pulmonary exacerbations.
Bhatt, Jayesh, Smyth, Alan R.
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