Results 11 to 20 of about 178,661 (314)

Acute Respiratory Barrier Disruption by Ozone Exposure in Mice

open access: yesFrontiers in Immunology, 2019
Ozone exposure causes irritation, airway hyperreactivity (AHR), inflammation of the airways, and destruction of alveoli (emphysema), the gas exchange area of the lung in human and mice.
Milena Sokolowska   +8 more
doaj   +1 more source

Development of a novel human intestinal model to elucidate the effect of anaerobic commensals on Escherichia coli infection

open access: yesDisease Models & Mechanisms, 2022
The gut microbiota plays a crucial role in protecting against enteric infection. However, the underlying mechanisms are largely unknown owing to a lack of suitable experimental models.
Conor J. McGrath   +5 more
doaj   +1 more source

Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis

open access: yesFrontiers in Physiology, 2018
Objective: Defective mucus production in the pancreas may be an important factor in the initiation and progression of chronic pancreatitis (CP), therefore we aimed to (i) investigate the qualitative and quantitative changes of mucus both in human CP and ...
Anita Balázs   +20 more
doaj   +1 more source

Association of allergen signatures with individualized allergic phenotypes

open access: yesAllergology International
Background: Allergen sensitization patterns are heterogeneous, and their clinical relevance is often obscured by extensive cross-reactivity. We applied non-negative matrix factorization (NMF) to disentangle overlapping immunoglobulin E (IgE) signals and ...
Dachan Kim   +3 more
doaj   +1 more source

PEDIATRICIAN’S APPROACH TO THE CHOICE OF MEDICATION AGAINST COUGH IN CHILDREN

open access: yesМедицинский совет, 2016
Cough is a common symptom in respiratory pathology which is associated with 30% of all visits to therapist and more than 50% to pediatrician, especially during the period of respiratory infection outbreak.
I. N. Zakharova, I. V. Berezhnaya
doaj   +1 more source

Mucus fishing syndrome

open access: yesBMJ Case Reports, 2022
Mucus fishing syndrome is a chronic inflammatory ocular surface condition characterised by repetitive self-extraction of mucous strands from the eye. A man in his 30s presented with bilateral ocular redness, itch, irritation, tearing and sticky mucoid discharge for 3 months.
Ryan L. J. Chiew   +2 more
openaire   +4 more sources

Spatiotemporal regulation by downstream genes of Prok2 in the olfactory system: from development to function

open access: yesFrontiers in Cell and Developmental Biology
IntroductionOlfaction is important for the quality of life; however, in Kallmann syndrome (KS), defective development results in olfactory dysfunction.
Bo-Ra Kim   +10 more
doaj   +1 more source

Inflammation-driven periostin in ECRS has contrasting effects on tissue structural integrity and osteitis

open access: yesFrontiers in Immunology
IntroductionEosinophilic chronic rhinosinusitis (ECRS) is a severe form of chronic rhinosinusitis characterized by type 2 inflammation, tissue remodeling, and bone thickening, known as osteitis.
Soo-In Kim   +16 more
doaj   +1 more source

Targeting TL1A/DR3 Signaling Offers a Therapeutic Advantage to Neutralizing IL13/IL4Rα in Muco-Secretory Fibrotic Disorders

open access: yesFrontiers in Immunology, 2021
Mucus secretion is an important feature of asthma that highly correlates with morbidity. Current therapies, including administration of mucolytics and anti-inflammatory drugs, show limited effectiveness and durability, underscoring the need for novel ...
Hope Steele   +5 more
doaj   +1 more source

The utiquity and many roles of exopolymers (EPS) in aquatic systems

open access: yesScientia Marina, 2004
Exopolymers (EPS) are produced by unicellular and multicellular organisms. They consist largely of polysaccharides that hydrate rapidly on contact with water and link to form gels.
Roger S. Wotton
doaj   +1 more source

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