Results 21 to 30 of about 170,590 (262)

Inflammation-driven periostin in ECRS has contrasting effects on tissue structural integrity and osteitis

open access: yesFrontiers in Immunology
IntroductionEosinophilic chronic rhinosinusitis (ECRS) is a severe form of chronic rhinosinusitis characterized by type 2 inflammation, tissue remodeling, and bone thickening, known as osteitis.
Soo-In Kim   +16 more
doaj   +1 more source

Targeting TL1A/DR3 Signaling Offers a Therapeutic Advantage to Neutralizing IL13/IL4Rα in Muco-Secretory Fibrotic Disorders

open access: yesFrontiers in Immunology, 2021
Mucus secretion is an important feature of asthma that highly correlates with morbidity. Current therapies, including administration of mucolytics and anti-inflammatory drugs, show limited effectiveness and durability, underscoring the need for novel ...
Hope Steele   +5 more
doaj   +1 more source

The utiquity and many roles of exopolymers (EPS) in aquatic systems

open access: yesScientia Marina, 2004
Exopolymers (EPS) are produced by unicellular and multicellular organisms. They consist largely of polysaccharides that hydrate rapidly on contact with water and link to form gels.
Roger S. Wotton
doaj   +1 more source

Cervicovaginal mucus barrier properties during pregnancy are impacted by the vaginal microbiome

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionMucus in the female reproductive tract acts as a barrier that traps and eliminates pathogens and foreign particles via steric and adhesive interactions.
Hannah C. Zierden   +28 more
doaj   +1 more source

Planarian Mucus: A Novel Source of Pleiotropic Cytotoxic and Cytostatic Agents against Cancer Cells

open access: yesBiomolecules
Biological evolution has generated a vast array of natural compounds produced by organisms across all domains. Among these, secondary metabolites, selected to enhance an organism’s competitiveness in its natural environment, make them a reservoir for ...
Gaetana Gambino   +3 more
doaj   +1 more source

Recent Insights into the Management of Inflammation in Asthma [Letter]

open access: yesJournal of Inflammation Research, 2021
Aleksandr Urakov,1,2,* Natalya Urakova1,* 1Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk City, Udmurt Republic, Russian Federation; 2Institute of Applied Mechanics, Udmurt Federal Research Center of the Ural ...
Urakov A, Urakova N
doaj  

Bacterial Communities in Tissues and Surficial Mucus of the Cold-Water Coral Paragorgia arborea

open access: yesFrontiers in Marine Science, 2018
Coral bacterial associates can play important functional roles for the holobiont, such as nitrogen cycling, nutrient processing, and supporting immunity.
Bradley A. Weiler   +2 more
doaj   +1 more source

The Role of Glycans in Bacterial Adhesion to Mucosal Surfaces: How Can Single-Molecule Techniques Advance Our Understanding?

open access: yesMicroorganisms, 2018
Bacterial adhesion is currently the subject of increased interest from the research community, leading to fast progress in our understanding of this complex phenomenon.
Cécile Formosa-Dague   +5 more
doaj   +1 more source

The biophysical principles underpinning muco-trapping functions of antibodies

open access: yesHuman Vaccines & Immunotherapeutics, 2022
In addition to the classical immunological functions such as neutralization, antibody-dependent cellular cytotoxicity, and complement activation, IgG antibodies possess a little-recognized and under-utilized effector function at mucosal surfaces ...
Alison Schaefer, Samuel K. Lai
doaj   +1 more source

Sobrerol: New Perspectives to Manage Patients with Frequent Respiratory Infections

open access: yesChildren, 2023
Respiratory tract infections (RTIs) are usually characterized by mucus hypersecretion. This condition may worsen and prolong symptoms and signs. For this reason, reducing mucus production and improving mucus removal represent relevant aspects of managing
Giorgio Ciprandi, Attilio Varriccchio
doaj   +1 more source

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