Results 11 to 20 of about 170,590 (262)
Current Biology, 2021 Mucus is a slimy hydrogel that lines the mucosal surfaces in our body, including the intestines, stomach, eyes, lungs and urogenital tract. This glycoprotein-rich network is truly the jack of all trades. As a barrier, it lubricates surfaces, protects our cells from physical stress, and selectively allows the passage of nutrients while clearing out ...
McShane, Abigail +7 more
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Biological modeling of mucus to modulate mucus barriers [PDF]
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2016 A recent study using a transgenic mouse, whose intestinal mucus contains a molecule made of 12 copies of a domain found in many gelling mucins, demonstrates that it is possible to strengthen mucus properties in situ, leading to promising new treatment strategies in diseases in which the mucosal barrier is impaired.
Desseyn, Jean-Luc +2 more
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Nature Reviews Microbiology, 2022 This study reports that SARS-CoV-2 binds to cilia and reprogrammes microvilli to promote replication in the nasal airway.
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Phage-encoded carbohydrate-interacting proteins in the human gut
Frontiers in Microbiology, 2023 In the human gastrointestinal tract, the gut mucosa and the bacterial component of the microbiota interact and modulate each other to accomplish a variety of critical functions.
Daniela Rothschild-Rodriguez +4 more
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Acute Respiratory Barrier Disruption by Ozone Exposure in Mice
Frontiers in Immunology, 2019 Ozone exposure causes irritation, airway hyperreactivity (AHR), inflammation of the airways, and destruction of alveoli (emphysema), the gas exchange area of the lung in human and mice.
Milena Sokolowska +8 more
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Disease Models & Mechanisms, 2022 The gut microbiota plays a crucial role in protecting against enteric infection. However, the underlying mechanisms are largely unknown owing to a lack of suitable experimental models.
Conor J. McGrath +5 more
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Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis
Frontiers in Physiology, 2018 Objective: Defective mucus production in the pancreas may be an important factor in the initiation and progression of chronic pancreatitis (CP), therefore we aimed to (i) investigate the qualitative and quantitative changes of mucus both in human CP and ...
Anita Balázs +20 more
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Association of allergen signatures with individualized allergic phenotypes
Allergology InternationalBackground: Allergen sensitization patterns are heterogeneous, and their clinical relevance is often obscured by extensive cross-reactivity. We applied non-negative matrix factorization (NMF) to disentangle overlapping immunoglobulin E (IgE) signals and ...
Dachan Kim +3 more
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PEDIATRICIAN’S APPROACH TO THE CHOICE OF MEDICATION AGAINST COUGH IN CHILDREN
Медицинский совет, 2016 Cough is a common symptom in respiratory pathology which is associated with 30% of all visits to therapist and more than 50% to pediatrician, especially during the period of respiratory infection outbreak.
I. N. Zakharova, I. V. Berezhnaya
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Frontiers in Cell and Developmental BiologyIntroductionOlfaction is important for the quality of life; however, in Kallmann syndrome (KS), defective development results in olfactory dysfunction.
Bo-Ra Kim +10 more
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