Mucus-Inspired Tribology, a Sticky Yet Flowing Hydrogel
The mucus blanket can trap foreign particles before they enter the lungs, while at the same time, it flows up to remove these particles. This manifests the dual nature of mucus: sticky, on one hand, and fluid, on the other.
Prabir K. Patra (1920082) +9 more
core +8 more sources
Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus. [PDF]
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Tollemeto M +5 more
europepmc +2 more sources
Functional characterization of a mucus-specific LPXTG surface adhesin from probiotic Lactobacillus rhamnosus GG [PDF]
In spite of the wealth of clinical evidence supporting the health benefits of Lactobacillus rhamnosus GG in humans, there is still a lack of understanding of the molecular mechanisms behind its probiosis.
Vos, W.M., de +17 more
core +1 more source
Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]
Background: Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
David A Groneberg +12 more
core +1 more source
A pilot study of the impact of high-frequency chest wall oscillation in chronic obstructive pulmonary disease patients with mucus hypersecretion [PDF]
Indranil Chakravorty1, Kamaljit Chahal2, Gillian Austin21St George's Hospital, London, 2East and North Hertfordshire NHS Trust, Lister Hospital and Primary Care Trust, Stevenage, Hertfordshire, UKIntroduction: Chronic obstructive pulmonary ...
Chahal, K +8 more
core +1 more source
The biochemical characterisation of respiratory mucus & mucins in normal, asthma & COPD [PDF]
Includes abstract.Includes bibliographical references (leaves 78-87).Airway mucus hyper-secretion is the main cause of mortality and morbidity in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) and is the leading ...
Trimmel, Astrid Joan
core +1 more source
Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis
Objective: Defective mucus production in the pancreas may be an important factor in the initiation and progression of chronic pancreatitis (CP), therefore we aimed to (i) investigate the qualitative and quantitative changes of mucus both in human CP and ...
Anita Balázs +20 more
doaj +1 more source
The isolation, purification, tissue localization and identification of a glycoprotein found in the crude mucus gel of patients with carcinoma of the stomach [PDF]
Includes bibliographical references (leaves 101-138).The thin layer of crude mucus lining the human gastric mucosa protects the delicate gastric epithelium from the high shear forces associated with digestion. Gastric mucus is composed largely of water (>
Nthato, Chirwa
core +1 more source
Gastric Output of Pancreatic Secretory Trypsin-Inhibitor Is Increased by Misoprostol [PDF]
Pancreatic secretory trypsin inhibitor (PSTI) is a potent protease inhibitor that also has growth promoting activity. It has recently been identified in the foveolar cells of the stomach, which secrete mucus.
Batten, J J +14 more
core +1 more source
Association of allergen signatures with individualized allergic phenotypes
Background: Allergen sensitization patterns are heterogeneous, and their clinical relevance is often obscured by extensive cross-reactivity. We applied non-negative matrix factorization (NMF) to disentangle overlapping immunoglobulin E (IgE) signals and ...
Dachan Kim +3 more
doaj +1 more source

