Results 21 to 30 of about 388,969 (398)

RoboCap: Robotic mucus-clearing capsule for enhanced drug delivery in the gastrointestinal tract

Sci. Robotics, 2022
Oral drug delivery of proteins is limited by the degradative environment of the gastrointestinal tract and poor absorption, requiring parenteral administration of these drugs. Luminal mucus represents the initial steric and dynamic barrier to absorption.
Shriya S. Srinivasan, Amro A. Alshareef, Alexandria Hwang, Ziliang Kang, J. Kuosmanen, K. Ishida, J. Jenkins, Sabrina Liu, W. Madani, J. Lennerz, A. Hayward, Joshua Morimoto, Nina Fitzgerald, R. Langer, G. Traverso   +14 more
semanticscholar   +1 more source

Influence of Prebiotic Activity of Agave salmiana Fructans on Mucus Production and Morphology Changes in Colonic Epithelium Cell of Healthy Wistar Rats

Frontiers in Plant Science, 2021
The beneficial health of evaluating prebiotic effect by the consumption of Agave salmiana fructans (A. salmiana fructans) was assessed in the epithelium of the cecum and proximal colon of Wistar rats fed at different doses for 35 days with regards to ...
Amneris Iraida Castillo Andrade, Erika García Chávez, Cecilia Rivera Bautista, Cuauhtemoc Oros Ovalle, Miguel Angel Ruiz Cabrera, Alicia Grajales Lagunes   +5 more
doaj   +1 more source

Slimy partners: the mucus barrier and gut microbiome in ulcerative colitis

Experimental and Molecular Medicine, 2021
Ulcerative colitis (UC) is a chronic recurrent intestinal inflammatory disease characterized by high incidence and young onset age. Recently, there have been some interesting findings in the pathogenesis of UC.
Jian Fang, Hui Wang, Yuping Zhou, Hui Zhang, Huiting Zhou, Xiaohong Zhang   +5 more
semanticscholar   +1 more source

Dissociation between Cervical Mucus and Urinary Hormones during the Postpartum Return of Fertility in Breastfeeding Women [PDF]

, 2018
Identifying the return of fertility with cervical mucus observations is challenging during the postpartum period. Use of urinary measurements of estrogen and progesterone can assist in understanding the return to fertility during this period.
Blackwell, Len, Bouchard, Thomas, Brown, Simon, Fehring, Richard, Parenteau-Carreau, Suzanne   +4 more
core   +2 more sources

Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori [PDF]

, 2015
Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H.
Azevedo, Nuno F, Braeckmans, Kevin, Dakwar, George, De Smedt, Stefaan, Figueiredo, Céu, Fontenete, Silvia, Forier, Katrien, Guimarães, Nuno, Leite, Marina, Remaut, Katrien, Santos, Rita, Stremersch, Stephan, Wengel, Jesper, Xiong, Ranhua   +13 more
core   +6 more sources

Characterization of Highly Mucus-Adherent Non-GMO Derivatives of Lacticaseibacillus rhamnosus GG

Frontiers in Bioengineering and Biotechnology, 2020
Lacticaseibacillus rhamnosus GG is one of the best studied lactic acid bacteria in the context of probiotic effects. L. rhamnosus GG has been shown to prevent diarrhea in children and adults and has been implicated to have mitigating or preventive ...
Pia Rasinkangas, Hanne L. P. Tytgat, Jarmo Ritari, Justus Reunanen, Seppo Salminen, Airi Palva, François P. Douillard, Willem M. de Vos, Willem M. de Vos, Willem M. de Vos   +9 more
doaj   +1 more source

A Comparison of the Fertile Phase As Determined by the Clearplan Easy Fertility Monitor™ and Self-Assessment of Cervical Mucus [PDF]

, 2004
The purpose of this study was to compare the fertile phase of the menstrual cycle as determined by the Clearplan Easy Fertility Monitor (CPEFM) with self-monitoring of cervical mucus.
Fehring, Richard, Raviele, Kathleen, Schneider, Mary   +2 more
core   +3 more sources

Feeding Behavior, Shrinking, and the Role of Mucus in the Cannonball Jellyfish Stomolophus sp. 2 in Captivity

Diversity, 2022
The importance of mucus produced by jellyfish species remains as understudied as their feeding behavior. Here, we study medusae under captivity, ascertain the role of mucus, and describe its feeding behavior.
Alicia Verónica Camacho-Pacheco, Laura Cristina Gómez-Salinas, Miguel Ángel Cisneros-Mata, Demetrio Rodríguez-Félix, Lourdes Mariana Díaz-Tenorio, Marco Linné Unzueta-Bustamante   +5 more
doaj   +1 more source

Hybrid Lipid/Polymer Nanoparticles to Tackle the Cystic Fibrosis Mucus Barrier in siRNA Delivery to the Lungs: Does PEGylation Make the Difference?

ACS Applied Materials and Interfaces, 2022
Inhaled siRNA therapy has a unique potential for treatment of severe lung diseases, such as cystic fibrosis (CF). Nevertheless, a drug delivery system tackling lung barriers is mandatory to enhance gene silencing efficacy in the airway epithelium.
G. Conte, Gabriella Costabile, Domizia Baldassi, V. Rondelli, R. Bassi, D. Colombo, Giulia Linardos, E. Fiscarelli, R. Sorrentino, A. Miro, F. Quaglia, P. Brocca, I. d’Angelo, Olivia M. Merkel, F. Ungaro   +14 more
semanticscholar   +1 more source

Phage-encoded carbohydrate-interacting proteins in the human gut

Frontiers in Microbiology, 2023
In the human gastrointestinal tract, the gut mucosa and the bacterial component of the microbiota interact and modulate each other to accomplish a variety of critical functions.
Daniela Rothschild-Rodriguez, Morgen Hedges, Merve Kaplan, Sercan Karav, Franklin L. Nobrega   +4 more
doaj   +1 more source