Results 131 to 140 of about 53,249 (182)

Is Asthma Remission a New Achievable Goal? A Review of the Current Drug‐Related Evidence and Predictors

Allergy, Volume 81, Issue 9, Page 3107-3129, September 2026.
ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin, Giulia Marcassa, Bianca Olivieri, Gianenrico Senna, Marco Caminati   +4 more
wiley   +1 more source

Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma

Allergy, Volume 81, Issue 9, Page 3261-3272, September 2026.
EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler, Sally E. Wenzel, Steve D. Groshong, Mario Castro, Ian D. Pavord, Klaus F. Rabe, Elizabeth Laws, Alexandre Jagerschmidt, Kaitlyn Gayvert, Sivan Harel, Jennifer D. Hamilton, Nikhil Amin, Lu Zhang, Heming Xing, Anissa Elfakir, Bema Coulibaly, Souâd Naimi, Sara Hamon, Paul J. Rowe, Frank Nestle, Danen M. Cunoosamy, Emanuele de Rinaldis, Leda P. Mannent   +22 more
wiley   +1 more source

Usefulness of Mepolizumab for Mucus Plugs

Internal Medicine
Hamakawa, Masamitsu, Ishida, Tadashi
openaire   +2 more sources

Targeting Airway Remodeling in Severe Asthma: Is There a Window of Opportunity for Biologic Therapy Predicting Effects Using Causal Artificial Intelligence?

Allergy, Volume 81, Issue 9, Page 3157-3170, September 2026.
ABSTRACT Airway remodeling is increasingly recognized as a major determinant of asthma progression, fixed airflow limitation, and long‐term morbidity, particularly in severe disease. Although biologic therapies have transformed outcomes by reducing exacerbations and systemic corticosteroid exposure, their potential to modify structural airway ...
Sebastiano Gangemi, Sara Manti, Johann Christian Virchow, Giorgio Walter Canonica   +3 more
wiley   +1 more source

Antipredatory Strategies of Anurans: An Updated Conceptual Review

Ethology, Volume 132, Issue 9, Page 662-708, September 2026.
To unravel the evolutionary dynamics of predator–prey interactions, we propose an updated, three‐tiered classification of anuran antipredatory strategies. By mapping non‐behavioral, individual, and group defenses across five functional phases, this integrative framework introduces the concept of synergetic coupling.
Ubiratã Ferreira Souza, Lucas Rosado Mendonça, Carlos Jared, L. Felipe Toledo   +3 more
wiley   +1 more source

Correlation of Aspergillus fumigatus Sensitization with Mucus Plugging in COPD [PDF]

Ying Luo,1,2 Jiaqi Ren,1,2 Long Liang,1,2 Jingge Qu,1,2 Chun Chang,1,2 Yongchang Sun1,2 1Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, People’s Republic of China; 2Research Center for Chronic Airway ...
Ren J, Qu J, Liang L, Luo Y, Chang C, Sun Y   +5 more
core  

Carbocisteine Reduces Airway Mucus Obstruction and Alters Inflammatory Cell Populations in a Model of Muco‐Obstructive Lung Disease

Immunology &Cell Biology, Volume 104, Issue 8, Page 833-844, September 2026.
Mice with a muco‐obstructive lung disease phenotype were treated with the mucoactive drug, carbocisteine, which resulted in reduced airway mucus and an alteration in the lung mononuclear cell population which was either as a direct effect of, or secondary to, improved mucus clearance.
Peter Ferris, Ryan Brown, Michael McKelvey, Daniel F. McAuley, Marcus A. Mall, Bronwen Connolly, Clifford C. Taggart   +6 more
wiley   +1 more source

Efficacy and Safety of Mechanical Insufflation–Exsufflation in Invasively Ventilated Critically Ill Adults: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Nursing in Critical Care, Volume 31, Issue 5, September 2026.
ABSTRACT Background Mechanical insufflation–exsufflation (MI–E) is increasingly used in invasively ventilated adults in the intensive care unit (ICU), yet its therapeutic efficacy and safety remain uncertain due to inconsistent evidence. Aim To synthesize evidence on the clinical efficacy and safety of MI–E in this population and to examine ...
Zhiqun Liu, Guiling Liao, Hui Wen, Xiaotong Han, Maiying Fan, Shuzhen Mao, Xiaohua Liu, Huan Wan   +7 more
wiley   +1 more source

Clinical Impact of Mepolizumab on Airway Mucus Plugs in Patients with Severe Asthma

Journal of Asthma and Allergy
Yu Hara,1 Naoya Tanabe,2 Satoshi Marumo,3,4 Kota Murohashi,1 Yusuke Hayashi,2 Mayu Nagata,4 Takuji Asada,5 Satoshi Nagaoka,1 Nobuaki Kobayashi,1 Toyohiro Hirai,2 Takeshi Kaneko1 1Department of Pulmonology, Yokohama City University Graduate School of ...
Hara Y, Tanabe N, Marumo S, Murohashi K, Hayashi Y, Nagata M, Asada T, Nagaoka S, Kobayashi N, Hirai T, Kaneko T   +10 more
doaj  

Mucus plugging

, 2017
openaire   +1 more source