Results 151 to 160 of about 53,249 (182)

Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction [PDF]

Journal of Clinical Investigation, 2018
The link between mucus plugs and airflow obstruction has not been established in chronic severe asthma, and the role of eosinophils and their products in mucus plug formation is unknown.
Sb Fain, Brett Elicker, Mario Castro
exaly   +2 more sources

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The viscoelastic properties of the cervical mucus plug

Acta Obstetricia et Gynecologica Scandinavica, 2014
AbstractObjectiveTo characterize the viscoelastic properties of cervical mucus plugs (CMPs) shed during labor at term.DesignExperimental research.SettingDepartment of Obstetrics and Gynecology, Aarhus University Hospital, Denmark.Population/SampleSpontaneously shed CMPs from 18 healthy women in active labor.MethodsViscoelastic properties of CMPs were ...
Bastholm, S.K., Becher, N., Stubbe, Peter Reimer, Chronakis, Ioannis S., Uldbjerg, N.; id_orcid 0000-0002-6449-6426   +4 more
openaire   +3 more sources

Antimicrobial factors in the cervical mucus plug

American Journal of Obstetrics and Gynecology, 2002
The cervical mucus plug is positioned between the microbe-rich vagina and the normally sterile uterine cavity, which suggests a host defense function, but few relevant data are available. We analyzed the composition and antimicrobial activity of cervical mucus plugs.Cervical mucus plugs were collected from healthy women at delivery.
Hein, Merete, Valore, Erika V, Helmig, Rikke Bek, Uldbjerg, Niels; id_orcid 0000-0002-6449-6426, Ganz, Tomas   +4 more
openaire   +3 more sources

The cervical mucus plug: Structured review of the literature

Acta Obstetricia et Gynecologica Scandinavica, 2009
AbstractThe cervical mucus plug is a large, complex structure within the cervical canal that is shed shortly before or during labor. We propose that the cervical mucus plug fulfills critical ‘gate‐keeper’ functions based on its physical and immunologic properties, which help prevent ascending infection and preterm labor.
Becher, Naja, Waldorf, Kristina Adams, Hein, Merete, Uldbjerg, Niels; id_orcid 0000-0002-6449-6426   +3 more
openaire   +2 more sources

Tension ball valve mucus plug in asthma

The American Journal of Medicine, 1985
This report describes a patient with status asthmaticus and respiratory failure in whom profound hypoxemia developed during mechanical ventilation. During the hypoxemic episode, breath sounds were absent over the left lung, and chest radiography revealed a hyperlucent left hemithorax with tension shift of the mediastinum to the right.
M S, Niederman, A, Gambino, J, Lichter, M, Weinblatt, A M, Fein   +4 more
openaire   +2 more sources

Effect of Benralizumab on Mucus Plugs in Severe Eosinophilic Asthma

International Archives of Allergy and Immunology, 2023
Introduction: Mucus plugs are associated with airway obstruction in severe asthma and are involved in the formation of activated eosinophils. Benralizumab, an anti-interleukin-5 receptor antibody, markedly reduces not only peripheral blood eosinophils but also airway eosinophils; however, its effects on mucus plugs have not been clarified.
Natsumi Sakai, Toshiyuki Koya, Yui Murai, Fumito Tsubokawa, Kentaro Tanaka, Shun Naramoto, Ami Aoki, Kenjiro Shima, Yosuke Kimura, Satoshi Watanabe, Takashi Hasegawa, Toshiaki Kikuchi   +11 more
openaire   +2 more sources

The Problem of Mucus Plugging in Children with Asthma

Journal of Asthma, 1985
The problem of mucus plugging of the lung was evaluated in 73 asthmatic children who had suffered a total of 187 episodes. The condition presented in young children, mostly with severe asthma, without any specific precipitating factor other than a severe attack of wheezing.
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Mucus plugging as a cause of acute lobar overdistension

Pediatric Emergency Care, 2001
Acute lobar overdistension in children is usually indicative of foreign body aspiration, especially when a history of a choking episode is recalled. An unusual presentation of asthma as recurrent overdistension of the left lung in a toddler is described.
M, Bitsori, E, Galanakis, E, Paraskakis, C E, Papadakis, H, Kokori, S, Sbyrakis   +5 more
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Mucus plugging on CT and mortality in smokers

Monitoring airway disease, 2019
Background: Mucus dysfunction, a key pathophysiologic feature of chronic obstructive pulmonary disease (COPD), is characterized by increased mucus production and plug formation in the airways leading to airflow obstruction. Computed tomography (CT) has been recently used to identify mucus plugs, providing an alternative way to assess mucus dysfunction.
Yuka Okajima, Carolyn Come, Pietro Nardelli, Sushil Sonavane, Andrew Yen, Nath Hrudaya, Nina Terry, Scott Grumley, Asmaa Ahmed, Kathleen Jacobs, Seth Kligerman, George Washko, Raul San Jose, Alejandro A Diaz   +13 more
openaire   +1 more source

Clinical Aspects of Mucus and Mucous Plugging in Asthma

Journal of Asthma, 1985
Abnormalities in the production and transport of airway secretions play an important role in the pathophysiology of asthma, especially during acute exacerbations of the disease. The synthesis of mucus becomes disordered, and other constituents of airway contents, including eosinophils and shed bronchial epithelial cells, contribute to the abnormal ...
openaire   +2 more sources