Results 11 to 20 of about 401,690 (283)
Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic InflammationSummary [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2020 Background & Aims: Infections resulting from intestinal yeast and bacteria affect a large number of patients with deficits in absorptive or secretory epithelial transport mechanisms.
Rainelli Koumangoye +3 more
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CD147 increases mucus secretion induced by cigarette smoke in COPD [PDF]
BMC Pulmonary Medicine, 2019 Background CD147 is expressed in many tissues and is involved in many inflammatory diseases. Emerging evidence suggests that the overproduction of mucus is a malignant factor in chronic obstructive pulmonary disease (COPD), which results in severe airway
Qiao Yu +3 more
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Mucus-Inspired Tribology, a Sticky Yet Flowing Hydrogel
The mucus blanket can trap foreign particles before they enter the lungs, while at the same time, it flows up to remove these particles. This manifests the dual nature of mucus: sticky, on one hand, and fluid, on the other.
Prabir K. Patra (1920082) +9 more
core +8 more sources
Xenopus: An alternative model system for identifying muco-active agents. [PDF]
PLoS ONE, 2018 The airway epithelium in human plays a central role as the first line of defense against environmental contaminants. Most respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma, and respiratory infections, disturb normal muco ...
Hyo Jung Sim +5 more
doaj +1 more source
Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell FunctionSummary
Cellular and Molecular Gastroenterology and Hepatology, 2022 Background & Aims: One of the features of ulcerative colitis (UC) is a defect in the protective mucus layer. This has been attributed to a reduced number of goblet cells (GCs).
Varsha Singh +10 more
doaj +1 more source
Frontiers in Immunology, 2021 Mucus secretion is an important feature of asthma that highly correlates with morbidity. Current therapies, including administration of mucolytics and anti-inflammatory drugs, show limited effectiveness and durability, underscoring the need for novel ...
Hope Steele +5 more
doaj +1 more source
Colonic barrier function in ulcerative colitis - Interactions between ion and mucus secretion [PDF]
, 2012 Anion and mucus secretions have traditionally been looked upon as two separate parts of the epithelial defense system. The importance of anion secretion has been attributed to its role in creating the driving force for fluid secretion that flushes the ...
Anna Ermund +6 more
core +2 more sources
Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat [PDF]
, 2008 Background: Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases including acute and chronic ...
David A Groneberg +12 more
core +1 more source
Mucus secretions in Cnidarian, an ecological, adaptive and evolutive tool
Advances in Oceanography and Limnology, 2022 Mucus secretion provides an interface with unique and multifunctional properties between the epithelial cells of many aquatic organisms and their surrounding environment.
Serena Savoca +4 more
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Strategies for measuring airway mucus and mucins
Respiratory Research, 2019 Mucus secretion and mucociliary transport are essential defense mechanisms of the airways. Deviations in mucus composition and secretion can impede mucociliary transport and elicit airway obstruction. As such, mucus abnormalities are hallmark features of
Kalina R. Atanasova, Leah R. Reznikov
doaj +1 more source