Results 51 to 60 of about 401,690 (283)

Entamoeba histolytica-Induced Mucin Exocytosis Is Mediated by VAMP8 and Is Critical in Mucosal Innate Host Defense

mBio, 2017
Intestinal mucus secretion is critical in maintaining mucosal host defense against a myriad of pathogens by preventing direct association with the epithelium.
Steve Cornick, France Moreau, Herbert Y. Gaisano, Kris Chadee   +3 more
doaj   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Proton Pump Inhibitors and Mucus Secretion [PDF]

Digestive Diseases and Sciences, 2009
I have read with great interest the article by Sarosiek et al. [1] reporting a stimulatory effect of rabeprazole on esophageal mucin. The article describes a pharmacological property which may have a pivotal role in protecting the esophageal mucosa against gastro-esophageal reflux and which appears to be unique in comparison with other proton pump ...
openaire   +2 more sources

Bicuculline reversibly inhibits mucus secretion.

, 2018
Mucus secretion was analyzed in the presence of 50uM of bicuculline (A) or after changing the media without bicuculline at every 30 min (B). Mucus secretion was restored within 1 hour after removing bicuculline.
Hyo Jung Sim (4876189), Kyung-Jae Myung (4876192), Tae Joo Park (1567174), Hyun-Shik Lee (211229), Taejoon Kwon (411568), Sang-Hyun Kim (282188)   +5 more
core   +1 more source

A Geometrically Transient Platform for Bioelectronic Implants

Advanced Materials, EarlyView.
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik, John D. Goodwin, Atharv Naik, Philip Coatsworth, Ioi Chit Cheung, Farbod Amirghasemi, Anies Sohi, Ehsan Abedi, Tayeb Tadlaoui, Maral P. S. Mousavi, Andriy S. Kozlov, Victoria Salem, Andrew S. Cowburn, Firat Guder   +13 more
wiley   +1 more source

Collagen‐Based Gut‐on‐Chip for In Vitro Modeling of Intestinal Barrier Function and Host‐Pathogen Interactions

Advanced Materials Technologies, EarlyView.
A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García, Jacques Leng, Hugo de Oliveira, Pierre Nassoy, Karine Dementhon   +4 more
wiley   +1 more source

Airway mucus in infection

Frontiers in Physiology
The mucosa of the airways is under a near-constant barrage of contaminants, allergens, and pathogens that can accumulate and cause irritation or infection if not promptly removed.
Caitlin Costello, Caitlin Costello, Susan Birket, Susan Birket   +3 more
doaj   +1 more source

Perovskite Nanoparticles Toxicity Study on Airway Epithelial Cells

Nanoscale Research Letters, 2019
Research on the toxicity of nanoparticles has developed over recent years due to their increasing prevalence in common everyday materials. Various nanoparticles have been reported to promote and induce mucus secretion, which could potentially lead to ...
Shih-Ming Tsai, Maria Mesina, Tyler Goshia, Meng-Hsuen Chiu, Julia Young, Angelo Sibal, Wei-Chun Chin   +6 more
doaj   +1 more source

Activation of goblet cell Piezo1 alleviates mucus barrier damage in mice exposed to WAS by inhibiting H3K9me3 modification

Cell & Bioscience, 2023
Background Our recent studies found that intestinal mechanical signals can regulate mucus synthesis and secretion of intestinal goblet cells through piezo type mechanosensitive ion channel component 1 (Piezo1), but the detailed molecular mechanisms ...
Yan Xu, Yilin Xiong, Ying Liu, Gangping Li, Tao Bai, Gen Zheng, Xiaohua Hou, Jun Song   +7 more
doaj   +1 more source

Putative muco-active reagents affecting mucus secretion level.

, 2018
The mucus level in the media upon the treatment of increasing doses of individual chemicals was normalized to those of control embryos and plotted on the graph (left panel, n = 5).
Hyo Jung Sim (4876189), Kyung-Jae Myung (4876192), Tae Joo Park (1567174), Hyun-Shik Lee (211229), Taejoon Kwon (411568), Sang-Hyun Kim (282188)   +5 more
core   +1 more source