Results 11 to 20 of about 123 (77)

Genetic and antigenic variation of the bovine tick-borne pathogen Theileria parva in the Great Lakes region of Central Africa [PDF]

Parasites & Vectors, 2019
Background Theileria parva causes East Coast fever (ECF), one of the most economically important tick-borne diseases of cattle in sub-Saharan Africa. A live immunisation approach using the infection and treatment method (ITM) provides a strong long-term ...
Gaston S. Amzati, Appolinaire Djikeng, David O. Odongo, Herman Nimpaye, Kgomotso P. Sibeko, Jean-Berckmans B. Muhigwa, Maxime Madder, Nathalie Kirschvink, Tanguy Marcotty   +8 more
doaj   +2 more sources

Lack of evidence for safe vaccination with the Muguga cocktail in Sudan

Onderstepoort Journal of Veterinary Research, 2013
How to cite this article: Geysen, D. & Berkvens, D., 2013, ‘Lack of evidence for safe vaccination with the Muguga cocktail in Sudan’, Onderstepoort Journal of Veterinary Research 80(1), Art. #571, 1 page. http:// dx.doi.org/10.4102/ojvr.
Dirk Geysen, Dirk Berkvens
doaj   +4 more sources

Molecular and immunological characterisation of Theileria parva stocks which are components of the ‘Muguga cocktail’ used for vaccination against East Coast fever in cattle

Veterinary Parasitology, 2001
The 'Muguga cocktail' which is composed of three Theileria parva stocks Muguga, Kiambu 5 and Serengeti-transformed has been used extensively for live vaccination against East Coast fever in cattle in eastern, central and southern Africa. Herein we describe the molecular characterisation of the T. parva vaccine stocks using three techniques, an indirect
Richard P Bishop, Vishvanath Nene, Subhash Morzaria   +2 more
exaly   +4 more sources

Production and dose determination of the Infection and Treatment Method (ITM) Muguga cocktail vaccine used to control East Coast fever in cattle

Ticks and Tick-borne Diseases, 2016
The Infection and Treatment Method (ITM) of vaccination against the apicomplexan parasite Theileria parva has been used since the early 1970s and is still the only commercially available vaccine to combat the fatal bovine disease, East Coast fever (ECF).
Ekta Patel, Subhash Morzaria, Andrew R Peters   +2 more
exaly   +4 more sources

Partial Budgeting Analysis of Muguga Cocktail Vaccine on Pastoralists’ Cattle in Narok County, Kenya

The International Journal of Business & Management, 2023
A 3-month prospective cross-sectional study was carried out to determine partial budgeting analysis of infection and treatment method (ITM) using the Muguga cocktail vaccine on pastoralists calves in Narok district, Kenya. The study was carried out in Osupuko and Loita sub-counties in Narok County.
null Mukholi G.Tenesi, null Henry K. Kiara, null Philip M. Kitala, null J.M.Gathuma   +3 more
openaire   +1 more source

Assessment of the Safety and Efficacy of Muguga Cocktail Vaccine on Pastoralists’ Cattle in Narok County, Kenya

The International Journal of Science & Technoledge, 2023
A five-month prospective longitudinal clinical study was carried out to assess the safety and efficacy of infection and treatment method (ITM) using the Muguga cocktail vaccine on pastoralists' calves in Narok County, Kenya. The study was carried out in contrasting three sites.
null Mukholi Gabriel Tenesi, null Henry K. Kiara, null Philip M. Kitala, null J.M.Gathuma   +3 more
openaire   +1 more source

Registration of the East Coast Fever Infection and Treatment Method vaccine (Muguga cocktail) in East Africa [PDF]

, 2020
This paper describes the preparation and submission of the original registration dossier for the East Coast fever vaccine ECF ITM ‘Muguga cocktail’ in Kenya, Tanzania, Uganda and Malawi between 2007 and 2009. The process faced a series of challenges in that the ‘vaccine’ unconventionally comprises a formulation of three stocks of the
Peters, Andrew, Toye, Philip G., Spooner, Paul, Giulio, Giuseppe di, Lynen, Godelieve   +4 more
openaire   +2 more sources

Antigen gene and variable number tandem repeat (VNTR) diversity in Theileria parva parasites from Ankole cattle in south‐western Uganda: Evidence for conservation in antigen gene sequences combined with extensive polymorphism at VNTR loci

Transboundary and Emerging Diseases, Volume 67, Issue S1, Page 99-107, March 2020., 2020
Abstract Theileria parva is a tick‐transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buffalo (Syncerus caffer), causing a frequently fatal disease of cattle in eastern, central and southern Africa. A live vaccination procedure, known as infection and treatment method (ITM), the most frequently used version ...
Anne Nanteza, Isaiah Obara, Paul Kasaija, Elisa Mwega, Fredrick Kabi, Diaeldin A. Salih, Moses Njahira, Joyce Njuguna, David Odongo, Richard P. Bishop, Rob A. Skilton, Jabbar Ahmed, Peter‐Henning Clausen, George W. Lubega   +13 more
wiley   +1 more source

Development and Dosage Determination of the "Muguga Cocktail Vaccine": An "Infection and Treatment Method" (ITM) for Managing East Coast Fever in Cattle in Pakistan

, 2023
“Theileria parva” (TP), an “apicomplexan parasite” that causes “East Coast Fever” (ECF) in cattle, in Pakistan. East coast fever (ECF) is a disease spread by ticks that is thought to cause at least $300 million in annual economic losses. The production procedure & other facets of the vaccine have not been sufficiently standardised, despite the fact
Ahsaan Ullah, Saqib, Muhammad
openaire   +1 more source

The persistence of componentTheileria parvastocks in cattle immunized with the ‘Muguga cocktail’ live vaccine against East Coast fever in Uganda

Parasitology, 2004
The ‘Muguga cocktail’ live vaccine comprises threeTheileria parvastocks (Muguga, Kiambu 5 and the buffalo-derived Serengeti-transformed) and has been used extensively in Eastern, Central and Southern Africa with an infection and treatment protocol to protect cattle against East Coast fever.
Oura, C.A.L., Bishop, Richard P., Wampande, E.M., Lubega, G.W., Tait, A.   +4 more
openaire   +3 more sources