Results 21 to 30 of about 39,049 (96)

Molecular epidemiology of Theileria parva in Eastern Democratic Republic of Congo: Implications to the introduction of the Muguga Cocktail vaccine for East Coast Fever

open access: yesbioRxiv
Abstract East Coast Fever (ECF) is one of the most economically important tick-borne diseases of cattle in Eastern, Central, and Southern Africa, caused by the intracellular protozoan parasite Theileria parva ( T. parva ).
Walter Muleya   +8 more
openaire   +2 more sources

Insights into Theileria transmission-blocking vaccines for East Coast fever control: A disease with an “outdated vaccination approach”

open access: yesTicks and Tick-Borne Diseases
Instead of using the Infection and Treatment Method (ITM)-based vaccine, is it possible to control East Coast Fever (ECF) through blocking Theileria parva transmission in ticks and cattle? This review pursues this question.
C. Ndawula, Jr   +3 more
doaj   +2 more sources

The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence. [PDF]

open access: yesBMC Genomics, 2015
BackgroundThere are no commercially available vaccines against human protozoan parasitic diseases, despite the success of vaccination-induced long-term protection against infectious diseases. East Coast fever, caused by the protist Theileria parva, kills
Norling M   +12 more
europepmc   +3 more sources

Partial Budgeting Analysis of the Fifty Percent Reduction in Acaricide Use and Adoption of Infection and Treatment Method on Pastoralists’ Cattle in Narok County, Kenya

open access: yesThe International Journal of Science & Technoledge, 2023
A 3-month prospective cross-sectional and simulation study was carried out to determine a partial budgeting analysis of infection and treatment method (ITM) using the Muguga cocktail vaccine with the fifty percent reduction in acaricide use on ...
Dr. Mukholi Gabriel Tenesi
semanticscholar   +1 more source

Development and Dosage Determination of the "Muguga Cocktail Vaccine": An "Infection and Treatment Method" (ITM) for Managing East Coast Fever in Cattle in Pakistan

open access: yes, 2023
“Theileria parva” (TP), an “apicomplexan parasite” that causes “East Coast Fever” (ECF) in cattle, in Pakistan. East coast fever (ECF) is a disease spread by ticks that is thought to cause at least $300 million in annual economic losses. The production procedure & other facets of the vaccine have not been sufficiently standardised, despite the fact
Ahsaan Ullah, Muhammad Saqib
openaire   +2 more sources

Genotyping of Theileria parva populations in vaccinated and non-vaccinated cattle in Malawi

open access: yesParasitology, 2022
Abstract Theileria parva is an apicomplexan protozoan parasite that causes bovine theileriosis (East Coast Fever; ECF) in central, eastern and southern Africa. In Malawi, ECF is endemic in the northern and central regions where it has negatively affected
Elisha Chatanga   +7 more
semanticscholar   +1 more source

The biology of Theileria parva and control of East Coast fever - Current status and future trends.

open access: yesTicks and Tick-borne Diseases, 2016
Tremendous progress has been made over the last ten years on East Coast fever (ECF) research. Publication of a reference genome sequence of Theileria parva, the causative agent of ECF, has led to a more thorough characterization of the genotypic and ...
V. Nene   +5 more
semanticscholar   +1 more source

Multilocus genotyping of Theileria parva isolates associated with a live vaccination trial in Kenya provides evidence for transmission of immunizing parasites into local tick and cattle populations.

open access: yesTransboundary and Emerging Diseases, 2020
The live infection and treatment (ITM) vaccination procedure using the trivalent Muguga cocktail is increasingly being used to control East Coast fever, with potential implications for Theileria parva population genetic structure in the field ...
R. Bishop   +5 more
semanticscholar   +1 more source

Assessing the impact of East Coast Fever immunisation by the infection and treatment method in Tanzanian pastoralist systems.

open access: yesPreventive Veterinary Medicine, 2010
A field trial was carried out in a Maasai homestead to assess the impact of East Coast Fever (ECF) immunisation by the infection and treatment method (ITM) with the Muguga Cocktail on the occurrence of this disease in Tanzanian pastoralist systems. These
S. B. Martins   +4 more
semanticscholar   +1 more source

Epidemiological perspectives of ticks and tick-borne diseases in South Sudan: Cross-sectional survey results

open access: yesOnderstepoort Journal of Veterinary Research, 2012
A cross-sectional study was conducted between September and October 2010 in five states of South Sudan that were selected on the basis of the perceived risk of tick-borne diseases.
Fredrick M. Kivaria   +4 more
doaj  

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