Results 51 to 60 of about 13,394,408 (251)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Multi-Agent-Based Controller for Microgrids: An Overview and Case Study
Energies, 2023 A microgrid can be defined as a grid of interconnected distributed energy resources, loads and energy storage systems. In microgrid systems containing renewable energy resources, the coordinated operation of distributed generation units is important to ...
Necmi Altin +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Observer-Based PID Control Protocol of Positive Multi-Agent Systems
Mathematics, 2023 This paper proposes the observer-based proportional-integral-derivative control of positive multi-agent systems. First, a positive observer is constructed for the considered multi-agent systems in terms of a matrix decomposition approach.
Xiaogang Yang +3 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Niching In Evolutionary Multi-Agent Systems
Computer Science, 2013 Niching is a group of techniques used in evolutionary algorithms, useful inseveral types of problems, including multimodal or nonstationary optimiza-tion. This paper investigates the applicability of these methods to evolutionarymulti-agent systems (EMAS)
Daniel Krzywicki
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The Application of Ontologies in Multi-Agent Systems in the Energy Sector: A Scoping Review
Energies, 2019 Multi-agent systems are well-known for their expressiveness to explore interactions and knowledge representation in complex systems. Multi-agent systems have been applied in the energy domain since the 1990s.
Zheng Ma +5 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source