Results 61 to 70 of about 12,467,789 (199)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Observer-Based PID Control Protocol of Positive Multi-Agent Systems

Mathematics, 2023
This paper proposes the observer-based proportional-integral-derivative control of positive multi-agent systems. First, a positive observer is constructed for the considered multi-agent systems in terms of a matrix decomposition approach.
Xiaogang Yang, Mengxing Huang, Yuanyuan Wu, Siling Feng   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Organisational Abstractions for the Analysis and Design of Multi-Agent Systems

, 2000
The architecture of a multi-agent system can naturally be viewed as a computational organisation. For this reason, we believe organisational abstractions should play a central role in the analysis and design of such systems.
Jennings, N. R., Zambonelli F., Wooldridge M., Zambonelli, F., Jennings N. R., Wooldridge, M.   +5 more
core   +2 more sources

Niching In Evolutionary Multi-Agent Systems

Computer Science, 2013
Niching is a group of techniques used in evolutionary algorithms, useful inseveral types of problems, including multimodal or nonstationary optimiza-tion. This paper investigates the applicability of these methods to evolutionarymulti-agent systems (EMAS)
Daniel Krzywicki
doaj   +1 more source

A Review on Computational Trust Models for Multi-agent Systems [PDF]

, 2009
Trust plays important roles on effective interaction and cooperation for multi-agent systems(MAS). This study aims at finding out the current situation and future trends of computational trustfor multi-agent systems.
Yao, Shaowen, Yao, S, Lu, Joan, Yip, YJ, Lu, Gehao, Lu, J, Yip, Yau Jim, Lu, G, Joan Lu, Jim Yip, Gehao Lu, Shaowen Yao   +11 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Application of Ontologies in Multi-Agent Systems in the Energy Sector: A Scoping Review

Energies, 2019
Multi-agent systems are well-known for their expressiveness to explore interactions and knowledge representation in complex systems. Multi-agent systems have been applied in the energy domain since the 1990s.
Zheng Ma, Mette Jessen Schultz, Kristoffer Christensen, Magnus Værbak, Yves Demazeau, Bo Nørregaard Jørgensen   +5 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Robust explanations for human-neural multi-agent systems with formal verification

, 2023
The quality of explanations in human-agent interactions is fundamental to the development of trustworthy AI systems. In this paper we study the problem of generating robust contrastive explanations for human-neural multi-agent systems and introduce two ...
Lomuscio, Alessio, Leofante, Francesco
core   +1 more source