Results 41 to 50 of about 39,694 (292)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Harvesting living labs outcomes through learning pathways
Living labs have emerged as a long-term, collaborative approach to addressing complex societal challenges, such as sustainable land and water management and climate change adaption.
Astha Bhatta +2 more
doaj +1 more source
Potentials and barriers to land-based mitigation technologies and practices (LMTs)—a review
Land-based mitigation technologies and practices (LMTs) are critical for achieving the Paris Agreement’s aim of avoiding dangerous climate change by limiting the rise in average global surface temperatures.
Lokendra Karki +14 more
doaj +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Climate-induced hazards are becoming more frequent and severe, causing escalating economic losses worldwide. Consequently, climate change adaptation is increasingly necessary to protect people, nature and the economy.
Ignasi Cortés Arbués +4 more
doaj +1 more source
Public space is an essential element of cities as it offers several benefits. Due to its significance, there is much discussion of its design, development and use.
Dahae Lee
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The validity of simplifying gaming simulations
Simplifications of the real world affect the validity and reliability of gaming simulations. This challenges the application of gaming simulations as an instrument for experiential learning, reflective practices and data collection.
M.A. van Haaften +3 more
doaj +1 more source
Capabilities for advanced services: A multi-actor perspective [PDF]
Servitization involves manufacturers developing service offerings to grow revenue and profit. Advanced services, in particular, can facilitate a more service-focused organization and impact customers' business processes significantly. However, approaches to servitization are often discussed solely from the manufacturer's perspective; overlooking the ...
Vicky M. Story +4 more
openaire +4 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source

