Results 51 to 60 of about 334,889 (275)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Co-creation or Co-destruction: A Perspective of Online Customer Engagement Valence

Frontiers in Psychology, 2021
The increasing interest in online shopping in recent years has increased the importance of understanding customer engagement valence (CEV) in a virtual service network.
Junaid Siddique, Amjad Shamim, Muhammad Nawaz, Ibrahima Faye, Mobashar Rehman   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The European Union’s Multi-Level Cultural Diplomacy vis-à-vis the United States of America. Working Paper Series W-2018/7 [PDF]

, 2018
This paper examines how, to what extent and why the EU engages in cultural diplomacy vis-à-vis the US. While providing an empirical review of and conceptual reflection on the current state of the EU’s (including key member states’) efforts at employing ...
Schunz, Simon, Trobbiani, Riccardo
core  

The future of sovereignty in multilevel governance Europe: a constructivist reading [PDF]

, 2004
Multilevel governance presents a depiction of contemporary structures in EU Europe as consisting of overlapping authorities and competing competencies. By focusing on emerging non-anarchical structures in the international system, hence moving beyond the
Adler E., Adler E., Adler E., Anderson J., Bache I., Bartelson J., Berger P.L., Bernard N., Bull H., Caporaso J.A., Checkel J.T., Checkel J.T., Christiansen T., Christiansen T., Deutsch K.W., Deutsch K.W., Friedrichs J., Guzzini S., Hooghe L., Hooghe L., Howarth D., Jachtenfuchs M., Jachtenfuchs M., Jorgensen K.E., Kohler-Koch B., Kohler-Koch B., Kohler-Koch B., Krasner S.D., Kratochwil F., Marks G., Marks G., Marks G., Milward A.S., Puchala D.J., Rhodes R.A.W., Rhodes R.A.W., Risse-Kappen T., Rosamond B., Scharpf F.W., Searle J.R., Shaw J., Smith S., Waever O., Waever O., Walker R.B.J., Walker R.B.J., Walters W., Waltz K.N., Wendt A., Wendt A., Wendt A., Wendt A., Wendt A., Wendt A., Werner W.G.   +54 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Quand les acteurs faibles et absents s’immiscent dans la négociation environnementale

Territoire en Mouvement, 2011
Ecological disturbances force us to inquire, at both global and local levels : how to live together ? or more precisely, how to decide together ? On this aspect, we show that negotiation theories reveal their weaknesses when confronted to absent actors ...
Léa Sebastien
doaj   +1 more source

At the interface between the formal and informal, the actual and the real: a realist study protocol for governance and accountability practices in urban settings focusing on adolescent sexual and reproductive health and rights

International Journal for Equity in Health, 2022
Background This paper presents the protocol of a study that aims at exploring how different multi-level governance arrangements impact on sexual and reproductive health of adolescents living in informal settlements. The overall objective of this study is
Sara Van Belle
doaj   +1 more source

Decision Making and Value Realization in Multi-Actor e-Government Contexts

, 2016
In the last two decades, governments around the world have been implementing electronic services in order to create a range of public values and meet new demands from a variety of stakeholders. Such activities fall within the scope of the e-Government research field.
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source