Results 61 to 70 of about 12,474 (244)

LEGITIMASI KEKUASAAN ATAS SEJARAH KERUNTUHAN KERAJAAN MAJAPAHIT DALAM WACANA FOUCAULT

Walisongo: Jurnal Penelitian Sosial Keagamaan, 2016
The history of the collapse of the Majapahit showed the discourse of power. In this context  rule has been supporting a particular version of historical knowledge.
Muhammad Iqbal Birsyada
doaj   +1 more source

A Multi-Actor Collaborative Perspective: Investigating the Influence Pathways of Social Media Communication Compliance in the Context of the 15th Five-Year Plan

Accounting, Marketing and Organization
With the development of the digital economy and the proliferation of social media platforms, the compliance of corporate communication activities on these platforms has increasingly become a focal point of attention for both society and academia. Based on the theory of multi-stakeholder collaborative governance, this paper constructs a theoretical ...
Yingnuo Qi, Yunhui Cheng
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Nature-based health initiatives: A governance assessment tool based on indicators

Environmental and Sustainability Indicators
Nature-based health initiatives (NbHIs) are emerging as innovative approaches to promoting human well-being and environmental sustainability. However, a standardised method to evaluate the multi-actor, multi-level, and multi-sector governance required ...
Alessandra Rigo, Laura Secco, Elena Pisani   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Towards a more responsible sustainable innovation assessment and management culture in Europe

Engineering Management in Production and Services, 2017
This article presents new concepts and practical approaches resulting from the piloting of CASI-F - a common framework for the assessment and management of sustainable innovation (SI).
Popper Rafael, Popper Monika, Velasco Guillermo   +2 more
doaj   +1 more source

A governance approach for bim management across lifecycle and supply chains using mixed-modes of information delivery

Journal of Civil Engineering and Management, 2013
Built environment data is of varying nature embedding various forms of sensitivities with potential legal, contractual, intellectual property, and security implications. The paper presents a governance approach for managing multi-actor, multi-discipline,
Yacine Rezgui, Thomas Beach, Omer Rana
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source