Results 51 to 60 of about 51,709 (256)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Multi-attribute Group Decision Making Based on Granular Computing
工程科学与技术, 2013 :By simulating the process of human thinking,a solving method for multi-attribute group decision making problem based on granular computing was proposed. Firstly, mathematical description of granular computing structure model was discussed.
谭旭, 毛太田, 张少丁, 邹凯
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Ranking Alternatives on the Basis of a Dominance Intensity Measure [PDF]
, 2010 The additive multi-attribute utility model is widely used within MultiAttribute Utility Theory (MAUT), demanding all the information describing the decision-making situation. However, these information requirements can obviously be far too strict in many
Jiménez Martín, Antonio +3 more
core +1 more source
Cybernetics and Information Technologies, 2015 In this paper we investigate the dynamic multi-attribute group decision making problems, in which all the attribute values are provided by multiple decision makers at different periods. In order to increase the level of overall satisfaction for the final
Lin Wei, Yan Guangle, Shi Yuwen
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Research of Multi-Attribute Group Decision Making for Aviation Manufacturing Enterprise Material Supplier [PDF]
, 2011 With more and more applications of manufacturing resource in networked manufacturing, material supplier evaluation and selection will become increasingly important.
Dan Dan Xiong, Yang Yang, Hai Cheng Yang
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Linguistic Picture Fuzzy Dombi Aggregation Operators and Their Application in Multiple Attribute Group Decision Making Problem [PDF]
, 2019 The aims of this study are to propose the linguistic picture fuzzy Dombi (LPFD) aggregation operators and decision-making approach to deal with uncertainties in the form of linguistic picture fuzzy sets.
Muhammad Qiyas +3 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source