Results 71 to 80 of about 17,888,146 (299)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

ON RANKING OF TRAPEZOIDAL INTUITIONISTIC FUZZY NUMBERS AND ITS APPLICATION TO MULTI ATTRIBUTE GROUP DECISION MAKING

Journal of New Theory, 2015
− This paper focuses on the study of two characteristics of trapezoidal intuitionistic fuzzynumber (TRIFN), viz., Value index and Ambiguity index. Based on these two indexes, we develop analgorithm for ranking of trapezoidal intuitionistic fuzzy number ...
Debaroti Das, Pijus Kanti De
doaj  

Preference Evaluation and Recommendation of Athletes for National Traditional Sports Training Using an Intelligent Method Based on Picture Fuzzy Knowledge

IEEE Access
In sports, athletes’ initial training is crucial for their whole career. Initial training at the relevant board athletes are professionally trained for national and international competitions.
Xiaoyu Cao, Han Liu
doaj   +1 more source

A Fuzzy Multi-Attribute Group Decision-Making for Screening the Strategic Factors of SWOT Matrix [PDF]

پژوهش‌های مدیریت عمومی, 2011
The matrix of SWOT is one of well known tools for analyzing strategic cases in the process of strategic management. If used correctly, it can provide a good basis for successful strategy formulation.
doaj   +1 more source

MULTIMOORA strategy for solving multi-attribute group decision making (MAGDM) in trapezoidal neutrosophic number environment

CAAI Transactions on Intelligence Technology, 2020
The main purpose of this study is to bring in a new extension of multi-objective optimisation on the basis of ratio analysis plus full multiplicative form (MULTIMOORA) in trapezoidal neutrosophic number (TrNN) environment.
Surapati Pramanik, Rama Mallick, Rama Mallick   +2 more
doaj   +1 more source

Applications of Multi Attribute Decision making problem [PDF]

The method of generating intention with the scope of impact is called the decision making. It is the process which an unique or a group evaluates solutions and alternatives in order to found the most politic option while inspecting the problems or ...
Shoba P., Kavitha S., K. Selvakumari, S. Kavitha, Selvakumari K., P. Shoba   +5 more
core   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Decision-making Strategies and Performance among Seniors [PDF]

Using paper and pencil experiments administered in senior centers, we examine decision-making performance in multi-attribute decision problems. We find a significant decline in performance with age due to reduced reliance on common heuristics among our ...
Mikhael Shor, Tibor Besedes, Cary Deck, Sudipta Sarangi   +3 more
core  

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source