Results 71 to 80 of about 51,709 (256)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Modelling and optimizing multiple attribute decisions by using fuzzy sets [PDF]

open access: yes
The purpose of this paper is to present a coherent perspective of modeling and optimizing multiple attribute decisions by using fuzzy sets. In management practice we face most of the time the situation in which a problem have several possible solutions ...
Adina NEGRUSA, Gh. Gh. IONESCU
core  

Variable Sociability in Agent-Based Decision Making [PDF]

open access: yes, 1999
Multi-agent system research is concerned with the issues surrounding the performance of collections of interacting agents. A major concern, therefore, is with the design of the decision making mechanism that the individual agents employ in order to ...
Jennings, N. R.   +5 more
core   +1 more source

MULTIMOORA strategy for solving multi-attribute group decision making (MAGDM) in trapezoidal neutrosophic number environment

open access: yesCAAI Transactions on Intelligence Technology, 2020
The main purpose of this study is to bring in a new extension of multi-objective optimisation on the basis of ratio analysis plus full multiplicative form (MULTIMOORA) in trapezoidal neutrosophic number (TrNN) environment.
Surapati Pramanik   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

ON RANKING OF TRAPEZOIDAL INTUITIONISTIC FUZZY NUMBERS AND ITS APPLICATION TO MULTI ATTRIBUTE GROUP DECISION MAKING

open access: yesJournal of New Theory, 2015
− This paper focuses on the study of two characteristics of trapezoidal intuitionistic fuzzynumber (TRIFN), viz., Value index and Ambiguity index. Based on these two indexes, we develop analgorithm for ranking of trapezoidal intuitionistic fuzzy number ...
Debaroti Das, Pijus Kanti De
doaj  

Preference Evaluation and Recommendation of Athletes for National Traditional Sports Training Using an Intelligent Method Based on Picture Fuzzy Knowledge

open access: yesIEEE Access
In sports, athletes’ initial training is crucial for their whole career. Initial training at the relevant board athletes are professionally trained for national and international competitions.
Xiaoyu Cao, Han Liu
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

VIKOR Method for Interval Neutrosophic Multiple Attribute Group Decision-Making [PDF]

open access: yes, 2018
In this paper, we will extend the VIKOR (VIsekriterijumska optimizacija i KOmpromisno Resenje) method to multiple attribute group decision-making (MAGDM) with interval neutrosophic numbers (INNs). Firstly, the basic concepts of INNs are briefly presented.
Cun Wei (3958535)   +2 more
core   +1 more source

Pythagorean Fuzzy Interaction Muirhead Means with Their Application to Multi-Attribute Group Decision-Making

open access: yesInformation, 2018
Due to the increased complexity of real decision-making problems, representing attribute values correctly and appropriately is always a challenge. The recently proposed Pythagorean fuzzy set (PFS) is a powerful and useful tool for handling fuzziness and ...
Yuan Xu, Xiaopu Shang, Jun Wang
doaj   +1 more source

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