Results 81 to 90 of about 430,228 (297)

MULTIMOORA strategy for solving multi-attribute group decision making (MAGDM) in trapezoidal neutrosophic number environment

open access: yesCAAI Transactions on Intelligence Technology, 2020
The main purpose of this study is to bring in a new extension of multi-objective optimisation on the basis of ratio analysis plus full multiplicative form (MULTIMOORA) in trapezoidal neutrosophic number (TrNN) environment.
Surapati Pramanik   +2 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Can models be useful for deciding to convert to organic fruit growing ? An introduction to the discussion [PDF]

open access: yes, 2008
Modern high-input agriculture has produced great increases in crop yields but social and environmental costs have also been high. Over the past decades, sustainability has become more and more a guiding principle in agriculture.
Warlop, F.
core  

Hybrid automata dicretising agents for formal modelling of robots

open access: yes, 2011
Some of the fundamental capabilities required by autonomous vehicles and systems for their intelligent decision making are: modelling of the environment and forming data abstractions for symbolic, logic based reasoning.
Molnar, Levente, Veres, S.M.
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

ON RANKING OF TRAPEZOIDAL INTUITIONISTIC FUZZY NUMBERS AND ITS APPLICATION TO MULTI ATTRIBUTE GROUP DECISION MAKING

open access: yesJournal of New Theory, 2015
− This paper focuses on the study of two characteristics of trapezoidal intuitionistic fuzzynumber (TRIFN), viz., Value index and Ambiguity index. Based on these two indexes, we develop analgorithm for ranking of trapezoidal intuitionistic fuzzy number ...
Debaroti Das, Pijus Kanti De
doaj  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

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