Results 81 to 90 of about 51,709 (256)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The induced 2-tuple linguistic generalized OWA operator and its application in linguistic decision making [PDF]

open access: yes
We present the induced 2-tuple linguistic generalized ordered weighted averaging (2-TILGOWA) operator. This new aggregation operator extends previous approaches by using generalized means, order-inducing variables in the reordering of the arguments and ...
Jose M. Merigo Lindahl   +1 more
core   +1 more source

Probabilistic Linguistic Multiple Attribute Group Decision-Making Based on a Choquet Operator and Its Application in Supplier Selection [PDF]

open access: yes
As an enhanced version of traditional linguistic term sets, Probabilistic Linguistic Term Sets (PLTS) incorporate probabilistic information, thereby offering a more robust approach to Multiple Attribute Group Decision-Making (MAGDM) and significantly ...
Xin Liang, Weijia Kang, Yan Peng
core   +1 more source

A Fuzzy Multi-Attribute Group Decision-Making for Screening the Strategic Factors of SWOT Matrix [PDF]

open access: yesپژوهش‌های مدیریت عمومی, 2011
The matrix of SWOT is one of well known tools for analyzing strategic cases in the process of strategic management. If used correctly, it can provide a good basis for successful strategy formulation.
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

A new fuzzy multi-attribute group decision-making method based on TOPSIS and optimization models [PDF]

open access: yes, 2023
In this paper, a new method based on TOPSIS and optimization models is proposed for multi-attribute group decision-making in the environment of interval-valued intuitionistic fuzzy sets.Firstly, by minimizing the sum of differences between individual ...
Zhang, Shiquan   +3 more
core   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

NC-TODIM-Based MAGDM under a Neutrosophic Cubic Set Environment

open access: yesInformation, 2017
A neutrosophic cubic set is the hybridization of the concept of a neutrosophic set and an interval neutrosophic set. A neutrosophic cubic set has the capacity to express the hybrid information of both the interval neutrosophic set and the single valued ...
Surapati Pramanik   +3 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

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