Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Comparison of different Multiple-criteria decision analysis methods in the context of conceptual design: application to the development of a solar collector structure [PDF]
, 2014 At each stage of the product development process, the designers are facing an important task which consists of decision making. Two cases are observed: the problem of concept selection in conceptual design phases and, the problem of pre-dimensioning once
EL AMINE, Mehdi +2 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
An MAGDM Approach Combining Numerical Values with Uncertain Linguistic Information and Its Application in Evaluation of R&D Projects Xin-Bao Liu , Feng Pei , Jian-Bo Yang , Shan-Lin Yang [PDF]
International Journal of Computational Intelligence Systems, 2010 In multi-attribute group decision making (MAGDM) problems, decision attributes of alternatives are often considered as with quantitative and qualitative information.
Xin-Bao Liu +3 more
doaj +1 more source
Green Supplier Selection Based on Sequential Group Three-Way Decision Making
Mathematics, 2023 Environmental protection and sustainable development have become the consensus of all countries in the world. Enterprises must pay attention to the impact on the environment in their operations.
Jiekun Song, Xueli Leng, Zhicheng Liu
doaj +1 more source
Multi-attribute Group Decision Making Based on Granular Computing
工程科学与技术, 2013 :By simulating the process of human thinking,a solving method for multi-attribute group decision making problem based on granular computing was proposed. Firstly, mathematical description of granular computing structure model was discussed.
谭旭, 毛太田, 张少丁, 邹凯
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Probabilistic Hesitant Intuitionistic Linguistic Term Sets in Multi-Attribute Group Decision Making [PDF]
Symmetry, 2018 Decision making is the key component of people’s daily life, from choosing a mobile phone to engaging in a war. To model the real world more accurately, probabilistic linguistic term sets (PLTSs) were proposed to manage a situation in which several possible linguistic terms along their corresponding probabilities are considered at the same time ...
M. G. Abbas Malik +3 more
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source