Results 51 to 60 of about 17,888,146 (299)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2023 In this article, we have proposed a multi-attribute group decision making (MAGDM) with a new scenario or new condition named Chaotic MAGDM, in which not only the weights of the decision makers (DMs) and the weights of the decision attributes are ...
Fu Zhang, Weimin Ma
core +1 more source
An MAGDM Approach Combining Numerical Values with Uncertain Linguistic Information and Its Application in Evaluation of R&D Projects Xin-Bao Liu , Feng Pei , Jian-Bo Yang , Shan-Lin Yang [PDF]
International Journal of Computational Intelligence Systems, 2010 In multi-attribute group decision making (MAGDM) problems, decision attributes of alternatives are often considered as with quantitative and qualitative information.
Xin-Bao Liu +3 more
doaj +1 more source
Multi-attribute Group Decision Making Based on Granular Computing
工程科学与技术, 2013 :By simulating the process of human thinking,a solving method for multi-attribute group decision making problem based on granular computing was proposed. Firstly, mathematical description of granular computing structure model was discussed.
谭旭, 毛太田, 张少丁, 邹凯
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Green Supplier Selection Based on Sequential Group Three-Way Decision Making
Mathematics, 2023 Environmental protection and sustainable development have become the consensus of all countries in the world. Enterprises must pay attention to the impact on the environment in their operations.
Jiekun Song, Xueli Leng, Zhicheng Liu
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Cybernetics and Information Technologies, 2015 In this paper we investigate the dynamic multi-attribute group decision making problems, in which all the attribute values are provided by multiple decision makers at different periods. In order to increase the level of overall satisfaction for the final
Lin Wei, Yan Guangle, Shi Yuwen
doaj +1 more source