Results 61 to 70 of about 16,897,989 (294)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Probabilistic Hesitant Intuitionistic Linguistic Term Sets in Multi-Attribute Group Decision Making [PDF]
Symmetry, 2018 Decision making is the key component of people’s daily life, from choosing a mobile phone to engaging in a war. To model the real world more accurately, probabilistic linguistic term sets (PLTSs) were proposed to manage a situation in which several possible linguistic terms along their corresponding probabilities are considered at the same time ...
M. G. Abbas Malik +3 more
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
International Journal of Computational Intelligence SystemsThis paper introduces a novel arctangent-based interval-valued intuitionistic fuzzy entropy function designed to address multi-attribute group decision-making problems, particularly in situations where attribute weights are either completely unknown or ...
Jian Zheng, Minggao Dong
doaj +1 more source
Improving consistency evaluation in fuzzy multi-attribute pairwise comparison-based decision-making methods [PDF]
, 2014 A typical approach to handle the complexity of multi-faceted decision-making problems is to use multi-attribute decision-making (MADM) methods based on pairwise comparisons.
Shams, Farhad +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Possibility Method for Triangular Intuitionistic Fuzzy Multi-attribute Group Decision Making with Incomplete Weight Information [PDF]
International Journal of Computational Intelligence Systems, 2014 Triangular intuitionistic fuzzy numbers (TIFNs) are a special kind of intuitionistic fuzzy sets (IFSs) on a real number set. TIFNs are useful to deal with ill-known quantities in decision data and decision making problems themselves.
Shu-Ping Wan, Jiu-Ying Dong
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source