Results 41 to 50 of about 7,434 (257)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Multi Attribute Utility Theory (Death) Method In The Decision Of The Distributor Distributor Selection (Metode Multi Attribute Utility Theory (Maut) Dalam Keputusan Pemilihan Distributor Barang)

Jurnal KomtekInfo, 2020
Distributors are intermediaries who distribute products from factories to retailers. While the distributor of goods is the distributor of goods from factories to shops that need these goods. Incorrect selection of distributors can interfere with the sales process at the store.
Ritna Wahyuni, Sarjon Defit, Gunadi Widi Nurcahyo   +2 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Utility Value-Based User′s Preference Evaluation to Select Design Alternatives for Customized Apartment Housing Remodeling

Journal of Asian Architecture and Building Engineering, 2018
As an alternative method for architectural regeneration, remodeling is drawing keen attention. However, it has turned out that post-occupancy satisfaction is quite low.
Eunhwa Hong, Jaeho Cho, Jaeyoul Chun
doaj   +1 more source

Developing Stochastic Additive Utility Method (UTA) Considering the Possible Dependency among Criteria [PDF]

مدیریت صنعتی, 2019
Objective: One of the well-known methods as to Multi Attribute Utility Theory (MAUT) in the field of decision making is Utility Additive Method (UTA), which has been developed over time.
Mahnaz Hosseinzadeh, Mohammad Reza Mehrgan, Leili Aghaei Meibodi, Ezatollah Abbasian   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Batu Pulut Village Population Management Information System using the Multi Attribute Utility Theory (MAUT) Method

Sistemasi: Jurnal Sistem Informasi
Currently developing information technology can be used by village governments in order to increase the public reach of village governments for the community by providing easy access to information as well as developing better, transparent, effective and
Diana Asmarani Siregar, Samsudin Samsudin   +1 more
doaj   +1 more source

SISTEM PENDUKUNG KEPUTUSAN PEMILIHAN TENAGA KESEHATAN TELADAN PADA DINAS KESEHATAN KOTA TERNATE MENGGUNAKAN METODE MULTY ATTRIBUTE UTILITY THEORY (MAUT)

Patria Artha Technological Journal, 2019
Pemilihan tenaga kesehatan teladan merupakan kegiatan rutin setiap tahun oleh Dinas Kesehatan Kota Ternate yang bertujuan untuk memberi penghargaan kepada mereka yang sudah mengabdikan diri di PUSKESMAS.
Sitti Ningsih, Amal Khairan, Firman Tempola   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A new hybrid decision support tool for evaluating the sustainability of mining projects

International Journal of Mining Science and Technology, 2018
The integration of sustainable development challenges and opportunities into the decision making process during the design and/or implementation of multi-disciplinary mining projects is generally not supported by decision support systems (DSS).
S. Kamenopoulos, Z. Agioutantis, K. Komnitsas   +2 more
doaj   +1 more source