Results 51 to 60 of about 593,318 (265)

Multi-core Reachability for Timed Automata

open access: yes, 2012
Model checking of timed automata is a widely used technique. But in order to take advantage of modern hardware, the algorithms need to be parallelized. We present a multi-core reachability algorithm for the more general class of well-structured transition systems, and an implementation for timed automata.
Dalsgaard, Andreas Engelbredt   +4 more
openaire   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Binding of Pentagalloyl Glucose to Aortic Wall Proteins: Insights from Peptide Mapping and Simulated Docking Studies

open access: yesBioengineering, 2023
Pentagalloyl glucose (PGG) is currently being investigated as a non-surgical treatment for abdominal aortic aneurysms (AAAs); however, the molecular mechanisms of action of PGG on the AAA matrix components and the intra-luminal thrombus (ILT) still need ...
Dan Simionescu   +10 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

MIROS: A Hybrid Real-Time Energy-Efficient Operating System for the Resource-Constrained Wireless Sensor Nodes

open access: yesSensors, 2014
Operating system (OS) technology is significant for the proliferation of the wireless sensor network (WSN). With an outstanding OS; the constrained WSN resources (processor; memory and energy) can be utilized efficiently.
Xing Liu   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

SPOF—Slave Powerlink on FPGA for Smart Sensors and Actuators Interfacing for Industry 4.0 Applications

open access: yesEnergies, 2019
We here present a new PLC-POWERLINK industrial solution for Industry 4.0 applications. The proposed solution provides the capability to separate the sensing functionality from the PLC-side, in demand for the reconfigurable FPGA implementation.
Giacomo Valente   +6 more
doaj   +1 more source

A Flexible Heterogeneous Multi-Core Architecture [PDF]

open access: yes16th International Conference on Parallel Architecture and Compilation Techniques (PACT 2007), 2007
Peer ...
Pericàs Gleim, Miquel   +5 more
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A Gaussian Set Sampling Model for Efficient Shared Cache Profiling on Multi-Cores

open access: yesIEEE Access, 2019
The last level cache (LLC) has significant impact to system performance on modern multi-core processors. But as cache sizes reach several megabytes and more, the overhead of exploring performance on LLC greatly increases as well.
Yi Zhang   +3 more
doaj   +1 more source

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