Results 1 to 10 of about 46,954 (256)

Physical and biological characteristics of multi drug resistance (MDR): An integral approach considering pH and drug resistance in cancer [PDF]

Seminars in Cancer Biology, 2017
The role of the Warburg effect in cancer remains to be elucidated with a resurgence in research efforts over the past decade. Why a cancer cell would prefer to use energy inefficient glycolysis, leading to an alteration of pH both inside and outside of the cell, remains to be uncovered.
Ziad Omran, Paula Scaife, Simon Stewart   +2 more
exaly   +7 more sources

Multi-label classification for multi-drug resistance prediction of Escherichia coli

Computational and Structural Biotechnology Journal, 2022
Antimicrobial resistance (AMR) is a global health and development threat. In particular, multi-drug resistance (MDR) is increasingly common in pathogenic bacteria.
Yunxiao Ren, Trinad Chakraborty, Swapnil Doijad, Linda Falgenhauer, Jane Falgenhauer, Alexander Goesmann, Oliver Schwengers, Dominik Heider   +7 more
doaj   +3 more sources

MMP1 expression is activated by Slug and enhances multi-drug resistance (MDR) in breast cancer. [PDF]

PLoS One, 2017
High matrix metalloproteinase 1 (MMP1) expression is associated with enhanced breast cancer growth and metastasis and also might predict poor prognosis. In this study, we further investigated the functional role of MMP1 and how it is upregulated in multi-drug resistant (MDR) breast cancer cells.
Shen CJ, Kuo YL, Chen CC, Chen MJ, Cheng YM.   +4 more
europepmc   +6 more sources

Estimation of second line anti-tubercular drug susceptibility to Mycobacterium tuberculosis in clinical isolates [PDF]

Iranian Journal of Microbiology
Background and Objectives: Tuberculosis (TB) is an infectious disease that is among the most common in the world and is a leading cause of high mortality and morbidity. In India, there is very limited data on second line drug susceptibility testing. The
Harisree Sudersanan, Nikhilesh Menon Ravikumar, Baijayanti Mishra   +2 more
doaj   +2 more sources

Overcoming Cancer Multi-drug Resistance (MDR): Reasons, mechanisms, nanotherapeutic solutions, and challenges

Biomedicine and Pharmacotherapy, 2023
Multi-drug resistance (MDR) in cancer cells, either intrinsic or acquired through various mechanisms, significantly hinders the therapeutic efficacy of drugs. Typically, the reduced therapeutic performance of various drugs is predominantly due to the inherent over expression of ATP-binding cassette (ABC) transporter proteins on the cell membrane ...
Jiyuan Xu, Ranjith Kumar Kankala
exaly   +3 more sources

High Prevalence of Antimicrobial Resistance and Integron Gene Cassettes in Multi-Drug-Resistant Klebsiella pneumoniae Isolates From Captive Giant Pandas (Ailuropoda melanoleuca)

Frontiers in Microbiology, 2022
Multi-drug-resistant Klebsiella pneumoniae (MDR K. pneumonia) is increasingly being reported with corresponding increase in morbidity and mortality all over the world. However, limited information is available concerning MDR K. pneumonia in giant pandas.
Xia Yan, Xia Yan, Xiaoyan Su, Zhihua Ren, Xueyang Fan, Yunli Li, Chanjuan Yue, Mei Yang, Huidan Deng, Youtian Deng, Zhiwen Xu, Dongsheng Zhang, Lin Li, Rong Hou, Songrui Liu, Junliang Deng   +15 more
doaj   +1 more source

The impact of COVID-19 on the tuberculosis control activities in Addis Ababa

The Pan African Medical Journal, 2021
The first COVID-19 case was reported in Ethiopia on 13th March 2020 and series of announcements of set of measures, proclamation and directives have been enacted to fight the coronavirus pandemic.
Negussie Wodajo Beyene, Alemu Lakew Sitotaw, Ben Tegegn, Kidist Bobosha   +3 more
doaj   +1 more source

To Analyse the Resistance and Tolerance of several Multi Drug Resistant (MDR) Bacteria: [PDF]

, 2021
Antimicrobial resistance has become a serious problem for physicians around the world when it comes to treating patients. As a result, short-term research was carried out by us to determine the prevalence of multidrug-resistant (MDR) bacterial isolates and to study the mechanism of escaping the antibiotics.
Amartya Nandi, NAVNEET BATRA, KANAV SHARMA, BHASKAR R. PURI, BHAVANA M. PURI, KASHISH .   +5 more
openaire   +1 more source

Molecular and cellular paradigms of multidrug resistance in cancer

Cancer Reports, 2022
Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the ...
Foram U. Vaidya, Abu SufiyanChhipa, Vinita Mishra, Vishal Kumar Gupta, Shiv Govind Rawat, Ajay Kumar, Chandramani Pathak   +6 more
doaj   +1 more source

ABC transportome inventory of human pathogenic yeast Candida glabrata: Phylogenetic and expression analysis. [PDF]

PLoS ONE, 2018
ATP-binding cassette (ABC) is one of the two major superfamilies of transporters present across the evolutionary scale. ABC superfamily members came to prominence due to their ability to extrude broad spectrum of substrates and to confer multi drug ...
Sonam Kumari, Mohit Kumar, Nitesh Kumar Khandelwal, Priya Kumari, Mahendra Varma, Poonam Vishwakarma, Garima Shahi, Suman Sharma, Andrew M Lynn, Rajendra Prasad, Naseem A Gaur, Naseem A Gaur   +11 more
doaj   +1 more source