This work presents a positional isomer engineering strategy to create a microenvironment‐tolerant NIR‐II AIEgen. The para‐isomer exhibits optimized excited‐state dynamics, enabling potent Type‐I photodynamic activity under hypoxia along with photothermal conversion.
Wentian Zhang +12 more
wiley +1 more source
Contezolid in the Treatment of Multidrug‐Resistant Tuberculous Meningitis: A Case Report
ABSTRACT Multidrug‐resistant tuberculous meningitis (MDR‐TBM) has a high mortality rate, and treatment options are limited. Linezolid is recommended for refractory cases but often causes intolerable adverse reactions such as peripheral neuropathy. Contezolid, a novel oxazolidinone, has shown better safety profiles in preclinical and early clinical ...
Na Wang +10 more
wiley +1 more source
Prevalence of Pre-Extensively Drug-Resistant Tuberculosis (Pre XDR-TB) and Extensively Drug-Resistant Tuberculosis (XDR-TB) among Pulmonary Multidrug Resistant Tuberculosis (MDR-TB) at a Tertiary Care Center in Mumbai [PDF]
Background: India is a high burden country for Tuberculosis (TB). As per the World Health Organization (WHO) statistics, 24000 cases of Multi Drug Resistant (MDR) TB were diagnosed in India in 2014.
Unnati D. Desai , Jyotsna M. Joshi
doaj
From Food Waste to Valorized Nanomaterials: Sustainable Green Synthesis and Biomedical Applications
Food waste‐derived biomolecules act as natural reducing and stabilizing agents for the green synthesis of functional NPs with applications in antimicrobial systems, food packaging, biomedical technologies, and environmental remediation. ABSTRACT Food waste is a global issue, with billions of tons discarded and unutilized annually, causing economic ...
Siddhraj Rajput +8 more
wiley +1 more source
Tuberculosis recurrence and mortality after successful treatment: impact of drug resistance.
BACKGROUND: The DOTS (directly observed treatment short-course) strategy for tuberculosis (TB) control is recommended by the World Health Organization globally.
Cox, H +32 more
core +1 more source
The evaluation of the integrated client-centred intervention programme (ICIP) for clients with MDR-TB at DP Marais Hospital in the Western Cape [PDF]
Philosophiae Doctor - PhDAlthough TB is a curable communicable disease, poor adherence to TB treatment is a major barrier to TB control in South Africa as it increases the risks of morbidity, mortality and drug resistance at individual and community ...
Firfirey, Nousheena
core +1 more source
Background: To compare antimicrobial susceptibility pattern of fosfomycin and nitrofurantoin against multi-drug resistant gram negative uropathogens. Methods: In this descriptive study identification of 200 isolates of gram negative bacteria was done by ...
Shah M, Nadia Wali
doaj
Ferroptosis in breast cancer: From adipocyte–immune–iron regulation to therapeutic application
Ferroptosis in breast cancer is regulated by an integrated adipocyte–immune–iron network rather than by tumour‐intrinsic pathways alone. Adipocyte‐derived lipid substrates and redox metabolites, immune‐cell‐mediated cytokine signalling and iron‐dependent oxidative stress collectively shape a dynamic ferroptosis ecosystem that can shift tumours towards ...
Juan Sun, Yang Qu, Ru Yao, Yidong Zhou
wiley +1 more source
Molecular screening of new patients suspected for TB could help in the effective control of TB in Pakistan as it is a high TB burden country. It will be informative to understand the prevalence of multi drug resistance for a better drug regimen ...
Salma Hameed +5 more
doaj +1 more source
Molecular Genetic Analysis of Multi-drug Resistance in Indian Isolates of Mycobacterium tuberculosis
A total of 116 isolates from patients attending the out-patient department at the All India Institute of Medical Sciences, New Delhi and the New Delhi Tuberculosis Centre, New Delhi, India were collected.
Noman Siddiqi +7 more
doaj +1 more source

