Results 141 to 150 of about 46,954 (256)

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque   +4 more
wiley   +1 more source

Investigation of the intrinsic mechanism of drug resistance in multiple myeloma [PDF]

open access: yes, 2011
The focus of this thesis was to evaluate the mechanisms whereby myeloma cells develop intrinsic resistance with a focus on resistance in the context of bortezomib treatment.
Ooi, Melissa
core  

Nanoparticle‐Based Strategies to Combat Multidrug‐Resistant Bacteria: Mechanisms, Applications, and Future Perspectives

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Nanobiotics offer a promising strategy to combat antimicrobial resistance (AMR) and multidrug‐resistant (MDR) bacteria. Nanoparticles overcome traditional resistance mechanisms through unique physicochemical properties and multivalent interactions.
Akmal Zubair   +3 more
wiley   +1 more source

Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi   +3 more
wiley   +1 more source

Troglitazone reverses the multiple drug resistance phenotype in cancer cells

open access: yes, 2009
Gerald F Davies1, Bernhard HJ Juurlink2, Troy AA Harkness11Department of Anatomy and Cell Biology, College of Medicine, University of Saskatchewan, Saskatoon, Canada; 2College of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi ArabiaAbstract: A ...
Troy AA Harkness   +2 more
core  

Importância da investigação de proteínas de resistência ABCB1, ABCC1 e LRP e da proteína antiapoptótica Bcl-2 no diagnóstico e no prognóstico de leucemias agudas [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2010A resistência a múltiplas drogas é uma das maiores causas para a falha do tratamento das leucemias ...
Moraes, Ana Carolina Rabello de
core  

Antibiotic Resistance and Biofilm Gene Distribution in Colistin‐Resistant Acinetobacter baumannii

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Multicenter analysis of 144 clinical Acinetobacter baumannii isolates in Iran revealed high MDR/XDR rates and widespread biofilm formation (90.9%). Colistin resistance was linked to pmrAB overexpression, while blaPER‐1 was independently associated with strong biofilm production, highlighting chromosomal resistance mechanisms and biofilm as key drivers ...
Zainab Amer Hatem   +7 more
wiley   +1 more source

Characterisation of the vibrio cholerae antibiotic resistance var operon [PDF]

open access: yes, 2007
The discovery and use of antibiotics in the chemotherapy of bacterial infections has revolutionised medicine as it is today. Unfortunately, the progressive use of antibiotics has promoted the evolution of bacterial defences against these mediators and ...
Massam-Wu, Teresa
core  

Prevalence, Antimicrobial Resistance, and Resistance Gene Profiles of Extended‐Spectrum β‐Lactamase‐Producing Escherichia coli and Klebsiella pneumoniae Isolated From Quails in Sylhet, Bangladesh

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
This study investigated the molecular epidemiology and antimicrobial resistance of Escherichia coli and Klebsiella pneumoniae isolated from quails in Bangladesh. High prevalence of E. coli, including Shiga toxin‐producing strains, and widespread multidrug resistance were observed.
Md. Al Mamun   +10 more
wiley   +1 more source

The effects of new naphtoquinone and benzopyran derivatives studied in multi-drug resistant cancer cells

open access: yes, 2014
Multi-drug resistance (MDR) is a significant obstacle to the efficient treatment of cancer. Overexpression of membrane transporters P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP) is responsible for the classic mechanism of MDR –the ...
R. Cincinelli   +4 more
core  

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