Results 261 to 270 of about 3,358,336 (306)
Development of a novel multi-epitope vaccine for brucellosis prevention
HeliyonBrucellosis, a zoonotic disease caused by Brucella, presents a significant threat to both animal and human health. In animals, the disease can lead to infertility, miscarriage, and high fever, while in humans, symptoms may include recurrent fever, fatigue, sweating, hepatosplenomegaly, and joint and muscle pain following infection.
Jianbing Ding +2 more
exaly +4 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Immunoinformatics Protocol to Design Multi-Epitope Subunit Vaccines
2023With the development of scientific technologies, the accessibility of genomic data, computational tools, software, databases, and machine learning, the field of immunoinformatics has emerged as an effective technique for immunologists to design potential vaccines in a short time.
Parismita, Kalita +2 more
openaire +2 more sources
A candidate multi‐epitope vaccine against Lumpy skin disease
Transboundary and Emerging Diseases, 2022Lumpy skin disease (LSD) is a fulminant infectious disease that mostly affects cattle and causes considerable economic loss throughout the globe. This study was conducted to develop a new multi-epitope-based vaccine against LSD that can elicit immunological responses using an in silico reverse vaccinology approach.
Md Bashir Uddin +10 more
openaire +2 more sources
Immunology & Cell Biology, 1997
The evolution of vaccine strategies has seen a move from whole organisms to recombinant proteins, and further towards the ultimate in minimalist vaccinology, the epitope. The epitope‐based approach is clearly compelling as only a relatively tiny, but immunologically relevant, sequence is often capable of inducing protective immunity against a large and
openaire +2 more sources
The evolution of vaccine strategies has seen a move from whole organisms to recombinant proteins, and further towards the ultimate in minimalist vaccinology, the epitope. The epitope‐based approach is clearly compelling as only a relatively tiny, but immunologically relevant, sequence is often capable of inducing protective immunity against a large and
openaire +2 more sources
Design of multi-epitope, analogue-based cancer vaccines
Expert Opinion on Biological Therapy, 2003The current objective of our cancer programme is to develop an effective vaccine based on rationally designed T cell epitope analogues, for use in the adjuvant setting for non-small cell lung cancer (NSCLC) and colon cancer. Analogue epitopes, enhanced for either human leukocyte antigen (HLA) binding or T cell receptor (TCR) signalling, have been shown
John D, Fikes, Alessandro, Sette
openaire +2 more sources
The immune system as a neural network: A multi-epitope approach
Journal of Theoretical Biology, 1991The term "neural network" has been applied to arrays of simple activation units linked by weighted connections. If the connections are modified according to a defined learning algorithm, such networks can be trained to store and retrieve patterned information.
F T, Vertosick, R H, Kelly
openaire +2 more sources
Developing a multi-epitope vaccine against Helicobacter Pylori
Human ImmunologyHelicobacter pylori, a significant factor in the development of gastric cancer and peptic ulcers, poses challenges for drug development due to its resilience. Computational approaches offer potential solutions for effective vaccine development targeting its antigens while ensuring stability and safety.
Pedram Asadi, Sarabi +4 more
openaire +2 more sources
Design of a Helicobacter pylori multi-epitope vaccine based on immunoinformatics
Frontiers in ImmunologyHelicobacter pylori (H. pylori) is an infectious bacterium that colonizes the stomach of approximately half of the global population. It has been classified as a Group I carcinogen by the World Health Organization due to its strong association with an increased incidence of gastric cancer and exacerbation of stomach diseases.
Man Cui +9 more
exaly +4 more sources
Immunoplacental therapy, a potential multi-epitope cancer vaccine
Medical Hypotheses, 2006The field of tumor immunology has made great advancements in recent years. A retrospective analysis of previous vaccine strategies combined with present knowledge may provide additional insight in this treatment modality. This article provides a review of immunoplacental therapy (IPT), a cancer vaccine consisting of chorionic villi extractions from the
openaire +2 more sources