Results 1 to 10 of about 2,266 (210)

Reverse Vaccinology and Immunoinformatic Assisted Designing of a Multi-Epitopes Based Vaccine Against Nosocomial Burkholderia cepacia

Frontiers in Microbiology, 2022
Burkholderia cepacia is a Gram-negative nosocomial pathogen and is considered as a troublesome bacterium due to its resistance to many common antibiotics.
Aqel Albutti, Samia Al-Shouli, Noorah Alsowayeh   +2 more
exaly   +3 more sources

Immuno-Informatics Design of Multi-Epitope Vaccine Candidate Against <i>Anaplasma phagocytophilum</i> Using Major Surface Protein 4 (MSP-4) Antigen. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Bovine anaplasmosis is an intracellular tick‐borne, non‐contagious disease caused by gram‐negative bacteria of the family Anaplasmataceae and order Rickettsia. Anaplasma phagocytophilum is the etiological agent for human granulocytic anaplasmosis associated with severe health implications in parts of Europe and the USA and ...
Malgwi SA, Mani S, Kwoji ID, Adeleke VT, Adeleke MA, Okpeku M.   +5 more
europepmc   +2 more sources

“Immunoinformatic Identification of T-Cell and B-Cell Epitopes From Giardia lamblia Immunogenic Proteins as Candidates to Develop Peptide-Based Vaccines Against Giardiasis”

Frontiers in Cellular and Infection Microbiology, 2021
Giardiasis is one of the most common gastrointestinal infections worldwide, mainly in developing countries. The etiological agent is the Giardia lamblia parasite.
Carlos Velázquez, Adriana Garibay-Escobar, Gloria López-Romero   +2 more
exaly   +3 more sources

Immunoinformatic prediction of the pathogenicity of bovine viral diarrhea virus genotypes: implications for viral virulence determinants, designing novel diagnostic assays and vaccines development

Frontiers in Veterinary Science, 2023
IntroductionBovine viral diarrhea virus (BVDV) significantly impacts the bovine industries, both dairy and beef sectors. BVDV can infect various domestic and wild animals, most notably cattle.
Jamal Hussen, Anwar A G Al-Kubati, Maged Gomaa Hemida   +2 more
exaly   +3 more sources

Computational and Experimental Development of a Novel Multi-Epitope Vaccine Candidate Against Bovine Leukaemia Virus. [PDF]

Vet Med Sci
This study designs a novel multi‐epitope vaccine against bovine leukaemia virus using immunoinformatics. The construct demonstrates high antigenicity, stability, and strong receptor binding, indicating its potential as an effective recombinant vaccine candidate for further experimental validation .
Dini Y, Piri-Gharaghie T, Hamdi E, Goodarzi P, Ahmadi R.   +4 more
europepmc   +2 more sources

Immunoinformatic development of a multiepitope messenger RNA vaccine targeting lipoate protein ligase and dihydrolipoamide dehydrogenase proteins of Mycoplasma bovis in cattle [PDF]

Veterinary World
Background and Aim: Mycoplasma bovis is a significant pathogen in cattle, causing respiratory, reproductive, and mammary diseases, leading to substantial economic losses.
Dhafer Rasheed Al-Fetly, Dhama Alsallami, Amjed Alsultan   +2 more
doaj   +2 more sources

Advanced vaccinomic, immunoinformatic, and molecular modeling strategies for designing Multi- epitope vaccines against the Enterobacter cloacae complex

Frontiers in Immunology
The increasing and ongoing issue of antibiotic resistance in bacteria is of huge concern globally, mainly to healthcare facilities. It is now crucial to develop a vaccine for therapeutic and preventive purposes against the bacterial species causing ...
Hassan H. Alhassan
exaly   +3 more sources

Structural and immunogenic evaluation of silk proteins from Bombyx mori using advanced bioinformatics and deep learning for biomaterials applications [PDF]

Journal of Genetic Engineering and Biotechnology
Silk from Bombyx mori is a premier biomaterial. Yet, comprehensive structural and immunoinformatic characterization of its protein components—fibroin subunits (FibH, FibL, P25) and five sericin isoforms—remains incomplete, hindering rational design of ...
Andrés Puerta-González, Alejandro Soto-Ospina, Yuliet Montoya Osorio, John Bustamante-Osorno, Lina María Salazar-Peláez   +4 more
doaj   +2 more sources

Development of multi-epitope Cathepsin L driven short peptide vaccine against Fasciola gigantica [PDF]

Frontiers in Veterinary Science
Fasciolosis is an important zoonotic disease caused by Fasciola species (Fasciola spp.). Fasciola spp. infection has the potential to affect the livestock economy.
Supanan Chansap, Werachon Cheukamud, Thitikul Suthisintong, Pornanan Kueakhai, Narin Changklungmoa   +4 more
doaj   +2 more sources

Designing a Next-Generation Multiepitope-Based Vaccine against Staphylococcus aureus Using Reverse Vaccinology Approaches

Pathogens, 2023
Staphylococcus aureus is a human bacterial pathogen that can cause a wide range of symptoms. As virulent and multi-drug-resistant strains of S. aureus have evolved, invasive S.
Soumya Ranjan Mahapatra, Jyotirmayee Dey, T. Kiran Raj, Namrata Misra, Mrutyunjay Suar   +4 more
doaj   +1 more source