Immunogenicity of a Multi-Epitope DNA Vaccine Encoding Epitopes from Cu–Zn Superoxide Dismutase and Open Reading Frames of Brucella abortus in Mice [PDF]
Emilia Escalona+2 more
openalex +1 more source
Multi-parameter formulation development for an HIV-vaccine protein with direct validation of epitope binding integrity and stoichiometry [PDF]
Corinna Popp+6 more
openalex +1 more source
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. [PDF]
Broadly neutralizing monoclonal antibodies protect against infection with HIV-1 in animal models, suggesting that a vaccine that elicits these antibodies would be protective in humans.
Abernathy, Morgan E+31 more
core
Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli+3 more
wiley +1 more source
Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core
Multi-Epitope DC Vaccines with Melanoma Antigens for Immunotherapy of Melanoma
Background/Objectives: The revolution for the treatment of melanoma came with the approval of checkpoint blockade antibodies. However, a substantial proportion of patients show primary or secondary resistance to this type of immunotherapy, indicating the need for alternative therapeutic strategies.
Athanasios Seretis+14 more
openaire +2 more sources
The importance of science communication and public engagement to professional associations
Scientists have gathered in professional associations to promote science to the public. The American Association for Anatomy (AAA) has invested resources in programs to promote anatomical sciences to the public (high school level via the Anato‐Bee; all levels via Anatomy nights) and train scientists how to talk to the public (SciComm Bootcamp ...
Martine Dunnwald+2 more
wiley +1 more source
Designing B‐ and T‐cell multi‐epitope based subunit vaccine using immunoinformatics approach to control Zika virus infection [PDF]
Rajan Kumar Pandey+3 more
openalex +1 more source
Abstract In today's digital age, misinformation propagates rapidly through digital channels, blurring the lines between truth and fiction, and challenging the foundations of trust in information sources. Although affecting all spheres of life, misinformation poses a significant threat to workers highlighting a critical intersection between ...
Ashwani Malhotra+4 more
wiley +1 more source
Bioinformatics analysis of single and multi-hybrid epitopes of GRA-1, GRA-4, GRA-6 and GRA-7 proteins to improve DNA vaccine design against Toxoplasma gondii [PDF]
Minoo Shaddel+2 more
openalex +1 more source