Results 61 to 70 of about 79,223 (384)

Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting. [PDF]

, 2019
The goal of the Sexually Transmitted Infection Clinical Trial Group's Antimicrobial Resistance (AMR) in Neisseria gonorrhoeae (NG) meeting was to assemble experts from academia, government, nonprofit and industry to discuss the current state of research,
Bristow, Claire C, Cristillo, Anthony D, Dillon, Jo-Anne, Dong, Huan, Grad, Yonatan H, Kirkcaldy, Robert D, Klausner, Jeffrey D, Lawrence, Kenneth, Morris, Sheldon R, Nicholas, Robert A, Oldach, David, Rice, Peter A, Shafer, William Maurice, Torrone, Elizabeth, Wi, Teodora E, Zhou, Pei   +15 more
core   +1 more source

Evaluation of immunoprotective effects of PlpE multi-epitope protein incorporated within the aluminum hydroxide-adjuvanted inactivated vaccine against Pasteurella multocida infection in chickens

Poultry Science
Pasteurella multocida (Pm) is a major zoonotic pathogen that causes avian cholera in poultry, leading to significant economic losses. Although inactivated vaccines are commonly used, their immunogenicity is limited, highlighting the need for safer and ...
Xuelian Xiang, Yi Sun, Haili Zhang, Xinrui Wu, Jing Xia, Xinfeng Han, Yong Huang, Min Cui   +7 more
doaj   +1 more source

Protective CD8+ T-cell response against Hantaan virus infection induced by immunization with designed linear multi-epitope peptides in HLA-A2.1/Kb transgenic mice

Virology Journal, 2020
Background An effective vaccine that prevents disease caused by hantaviruses is a global public health priority, but up to now, no vaccine has been approved for worldwide use.
Ying Ma, Kang Tang, Yusi Zhang, Chunmei Zhang, Linfeng Cheng, Fanglin Zhang, Ran Zhuang, Boquan Jin, Yun Zhang   +8 more
doaj   +1 more source

Candidate Multi-Epitope Vaccine against Corona B.1.617 Lineage: In Silico Approach

Life, 2022
Various mutations have accumulated since the first genome sequence of SARS-CoV2 in 2020. Mutants of the virus carrying the D614G and P681R mutations in the spike protein are increasingly becoming dominant all over the world.
Mohamed G. Seadawy, Abdel Rahman N. Zekri, Aya A. Saeed, Emmanuel James San, Amr M. Ageez   +4 more
doaj   +1 more source

Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. [PDF]

, 2018
Nanoparticles have attracted considerable interest as cancer vaccine delivery vehicles for inducing sufficient CD8+ T cell-mediated immune responses to overcome the low immunogenicity of the tumor microenvironment.
Kim, Tae Il, Molino, Nicholas M, Neek, Medea, Nelson, Edward L, Tucker, Jo Anne, Wang, Szu-Wen   +5 more
core   +2 more sources

Designing multi-epitope monkeypox virus-specific vaccine using immunoinformatics approach

Journal of Infection and Public Health, 2023
Monkeypox virus is an enveloped DNA virus that belongs to Poxviridae family. The virus is transmitted from rodents to primates via infected body fluids, skin lesions, and respiratory droplets. After being infected with virus, the patients experience fever, myalgia, maculopapular rash, and fluid-filled blisters.
Sumera Zaib, Nehal Rana, null Areeba, Nadia Hussain, Hamad Alrbyawi, Ayed A. Dera, Imtiaz Khan, Mohammad Khalid, Ajmal Khan, Ahmed Al-Harrasi   +9 more
openaire   +3 more sources

Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles [PDF]

, 2011
Background: There is renewed interest in the development of poxvirus vector-based HIV vaccines due to the protective effect observed with repeated recombinant canarypox priming with gp120 boosting in the recent Thai placebo-controlled trial.
Anson, Donald S., Blanchard, Thomas, Blanchard, Tom J., Bridge, Simon H., Dennis, Mike J., Dowall, Stuart D., Getty, Brian, Sharpe, Sally A., Skinner, Michael A., Stewart, James P.   +9 more
core   +4 more sources

Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii

International Journal of Environmental Research and Public Health, 2022
Antibiotic resistance (AR) is the result of microbes’ natural evolution to withstand the action of antibiotics used against them. AR is rising to a high level across the globe, and novel resistant strains are emerging and spreading very fast. Acinetobacter baumannii is a multidrug resistant Gram-negative bacteria, responsible for causing severe ...
Miraj ud-din, Aqel Albutti, Asad Ullah, Saba Ismail, Sajjad Ahmad, Anam Naz, Muhammad Khurram, Mahboob ul Haq, Zobia Afsheen, Youness El Bakri, Muhammad Salman, Bilal Shaker, Muhammad Tahir ul Qamar   +12 more
openaire   +2 more sources

Computational design of a glycosylated multi-epitope vaccine against HAsV-1 and HAsV-2 astrovirus for acute gastroenteritis

Scientific Reports
Human astrovirus (HAsVs) is a significant viral agent responsible for acute gastroenteritis, primarily affecting children. Among HAsVs serotypes, HAsVs − 1 and HAsVs-2 are the most virulent serotypes, contributing to severe gastrointestinal infections ...
M. Naveed, Adeeba Ali, Tariq Aziz, Nouman Ali, H. M. Rehman, Ayaz Ali Khan, Taqweem ul Haq, Rania Ali EL HADI MOHAMED, Fahad Al‐Asmari, M. S. Alwethaynani, F. Al-Joufi, D. Fallatah   +11 more
semanticscholar   +1 more source

Design of Multi-Epitope Vaccine against SARS-CoV-2 [PDF]

Cybernetics and Information Technologies, 2020
Abstract The ongoing COVID-19 pandemic requires urgently specific therapeutics and approved vaccines. Here, the four structural proteins of the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2), the causative agent of COVID-19, are screened by in-house immunoinformatic tools to identify peptides acting as potential T-cell ...
Doytchinova Irini, Tchorbanov Andrey
openaire   +2 more sources