Results 91 to 100 of about 5,820,721 (304)

Focus groups as ethnography: the case of Prime Ministers’ Chiefs of Staff

, 2015
The purpose of this paper is to outline the current state of political and administrative ethnography in political science and public administration before suggesting that focus groups are a useful tool in the study of governing elites.
Rhodes, Roderick AW, Rhodes, R.A.W., Rhodes, Roderick, Tiernan, Anne, Tiernan, Anne-Maree   +4 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Reston Black Focus Goals

, 1969
Draft of official statements and goals for Reston Black Focus and a note informing membership of a tree planting in honor of Dr.
Reston Black Focus
core   +1 more source

LightMFF: A Simple and Efficient Ultra-Lightweight Multi-Focus Image Fusion Network

Applied Sciences
In recent years, deep learning-based multi-focus image fusion (MFF) methods have demonstrated remarkable performance. However, their reliance on complex network architectures often demands substantial computational resources, limiting practical ...
Xinzhe Xie, Zijian Lin, Buyu Guo, Shuangyan He, Yanzhen Gu, Yefei Bai, Peiliang Li   +6 more
doaj   +1 more source

Multi-Focus Image Fusion Algorithm in Sensor Networks

IEEE Access, 2018
Most imaging systems have a limited depth-of-field in the sensor networks that consist of multiple visual sensors. Due to different object distances, not every object can be clearly imaged by a single sensor.
Ying Tong, Jin Chen
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Universiti Utara Malaysia [PDF]

, 2013
Universiti Utara Malaysia (UUM) vice-chancellor Prof Datuk Dr Mohamed Mustafa Ishak (left), former Asean secretary-general Dr Surin Pitsuwan (centre) and UUM faculty member and conference co-director Dr Kamaruddin Abdulsomad attend the International ...
Malaysia, Focus
core  

Focus presuppositions

, 2008
This paper reviews notions related to focus and presupposition and addresses the hypothesis that focus triggers an existential presupposition. Presupposition projection behavior in certain examples appears to favor a presuppositional analysis of focus ...
Abusch, Dorit
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source