Results 81 to 90 of about 16,062,156 (297)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Multi-level Fusion of Audio and Visual Features for Speaker Identification [PDF]

open access: yes, 2005
This paper explores the fusion of audio and visual evidences through a multi-level hybrid fusion architecture based on dynamic Bayesian network (DBN), which combines model level and decision level fusion to achieve higher performance. In model level fusion, a new audio-visual correlative model (AVCM) based on DBN is proposed, which describes both the ...
Zhiyong Wu 0001   +2 more
openaire   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Multi-Level Feature Fusion Based Transfer Learning for Person Re-Identification

open access: yes, 2019
Most of the currently known methods treat person re-identification task as classification problem and used commonly neural networks. However, these methods used only high-level convolutional feature or to express the feature representation of pedestrians.
Yingzhi Chen (3745858)
core   +1 more source

SPL Features Quantification and Selection Based on Multiple Multi-Level Objectives

open access: yesApplied Sciences, 2019
Software Product Lines (SPLs) can aid modern ecosystems by rapidly developing large-scale software applications. SPLs produce new software products by combining existing components that are considered as features. Selection of features is challenging due
Fazal Qudus Khan   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

A Multi-Label Image Annotation With Multi-Level Tagging System

open access: yes, 2018
The content based image retrieval system retrieves relevant images based on image features. The lack of performance in the content based image retrieval system is due to the semantic gap.
Chitrakala S., Kalaivani Anbarasan
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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