Characteristics of DNA macro-alterations in breast cancer with liver metastasis before treatment
BMC Genomics, 2023 Background Whole-genome doubling (WGD) has been observed in 30% of cancers, followed by a highly complex rearranged karyotype unfavourable to breast cancer's outcome.
Yu Fan +7 more
doaj +1 more source
X-omics workshop: data standards and multi-omics data integration - EGA DAC data standard [PDF]
, 2020 Presentation given for X-omics online workshop series part 1 – "Data standards and multi-omics data integration", Thursday June 18th 2020, 10AM - 12PM CEST. This slide-set showcases the work of the Data Access Committee (DAC) from the LAB division of the
Jasmin K. Böhmer
core +1 more source
Integrated multi-omics analyses of microbial communities: a review of the current state and future directions [PDF]
, 2023 Integrated multi-omics analyses of microbiomes have become increasingly common in recent years as the emerging omics technologies provide an unprecedented opportunity to better understand the structural and functional properties of microbial communities.
Thilo Muth +4 more
core +1 more source
Integrating multi-omics data through deep learning for accurate cancer prognosis prediction [PDF]
, 2021 Background: Genomic information is nowadays widely used for precise cancer treatments. Since the individual type of omics data only represents a single view that suffers from data noise and bias, multiple types of omics data are required for accurate ...
Rao, J +5 more
core +1 more source
Multi-omics reveals mechanisms of resistance to potato root infection by Spongospora subterranea [PDF]
, 2022 The pathogen Spongospora subterranea infects potato roots and developing tubers resulting in tuber yield and quality losses. Currently, there are no fully effective treatments for disease control.
Wilson, Calum R. +4 more
core +1 more source
Multi-omics technologies applied to tuberculosis drug discovery [PDF]
, 2020 Multi-omics strategies are indispensable tools in the search for new anti-tuberculosis drugs. Omics methodologies, where the ensemble of a class of biological molecules are measured and evaluated together, enable drug discovery programs to answer two ...
Aaron Goff (16039727) +3 more
core +3 more sources
Osteosarcoma Multi-Omics Landscape and Subtypes
Cancers, 2022 Osteosarcoma (OS) is the most common primary bone malignancy that exhibits remarkable histologic diversity and genetic heterogeneity. The complex nature of osteosarcoma has confounded precise molecular categorization, prognosis, and prediction for this disease. In this study, we performed a comprehensive multiplatform analysis on 86 osteosarcoma tumors,
Shan Tang +3 more
openaire +2 more sources
MODIMO: Workshop on Multi-Omics Data Integration for Modelling Biological Systems [PDF]
, 2021 Multi-omics analysis aims at extracting previously uncovered biological knowledge by integrating information across multiple single-omic sources. Past approaches have focused on the simultaneous analysis of a small number of omic data sets.
Vincenzo Bonnici +5 more
core +1 more source
Annals of Human Biology, 2022 Background The analysis of Y chromosomal genetic markers is of great significance in human genetic fields related to male individuals. The Han nationality is the most populous ethnic group.
Hui Xu +6 more
doaj +1 more source
The Advent of Omics Sciences in Clinical Trials of Motor Neuron Diseases [PDF]
, 2022 The “omics revolution” has totally changed the scientific research approach and is contributing to the development of personalized therapies. In motor neuron diseases (MNDs), a set of complex, multifactorial, late-onset and chronic neurodegenerative ...
Cavallaro, Sebastiano +5 more
core +1 more source