Results 31 to 40 of about 2,476,048 (310)
Putting Proteomics Into Immunotherapy for Glioblastoma
Frontiers in Immunology, 2021 In glioblastoma, the most aggressive brain cancer, a complex microenvironment of heterogeneity and immunosuppression, are considerable hurdles to classify the subtypes and promote treatment progression. Treatments for glioblastoma are similar to standard
Liangyu Chen +5 more
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Assessment of Berberine as a Multi-target Antimicrobial: A Multi-omics Study for Drug Discovery and Repositioning [PDF]
, 2014 Postgenomics drug development is undergoing major transformation in the age of multi-omics studies and drug repositioning. Rather than applications solely in personalized medicine, omics science thus additionally offers a better understanding of a ...
SAYAR, NİHAT ALPAGU +1 more
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Learning from multi-omics data of cancer [PDF]
, 2022 Analysing multiple types of omics data is a keystone methodology in biomedical research nowadays. With the significant advances of high-throughput experimental technologies, an enormous amount of omics data with extremely high dimensionality are ...
Zhang, Xiaoyu
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Journal of Translational Medicine, 2023 Background Brachial plexus root avulsion (BPRA), a disabling peripheral nerve injury, induces substantial motoneuron death, motor axon degeneration and denervation of biceps muscles, leading to the loss of upper limb motor function.
Lin Wu +10 more
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Multi-Omics Approaches in Immunological Research [PDF]
Frontiers in Immunology, 2021 The immune system plays a vital role in health and disease, and is regulated through a complex interactive network of many different immune cells and mediators. To understand the complexity of the immune system, we propose to apply a multi-omics approach in immunological research.
Xiaojing Chu +13 more
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Multi-Omics factor analysis - a framework for unsupervised integration of multi-omic data sets
Molecular Systems Biology, 2017 Abstract Multi-omic studies promise the improved characterization of biological processes across molecular layers. However, methods for the unsupervised integration of the resulting heterogeneous datasets are lacking.
Argelaguet, Ricard +8 more
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Hereditas, 2022 Background Ancestry informative markers are regarded as useful tools for inferring the ancestral information of an individual, which have been widely used in the criminal investigations and population genetic studies.
Wei Cui +7 more
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Nature Microbiology, 2016 Multi-omic techniques are often seen as the future of microbiome studies. We argue that recent strategies for simplifying complex omic-derived data will need to be combined with improved cultivation techniques to pave the way towards a more targeted approach for understanding microbial communities.
Vilanova, Cristina, Porcar, Manuel
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The multi‐omics basis of potato heterosis [PDF]
Journal of Integrative Plant Biology, 2022 ABSTRACTHeterosis is a fundamental biological phenomenon characterized by the superior performance of hybrids over their parents. Although tremendous progress has been reported in seed crops, the molecular mechanisms underlying heterosis in clonally propagated crops are largely unknown. Potato (Solanum tuberosum L.) is the most important tuber crop and
Dawei Li +9 more
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Multi-omics approaches to improve malaria therapy [PDF]
, 2021 Malaria contributes to the most widespread infectious diseases worldwide. Even though current drugs are commercially available, the ever-increasing drug resistance problem by malaria parasites poses new challenges in malaria therapy. Hence, searching for
Zhou, Min +2 more
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