Results 81 to 90 of about 2,476,048 (310)

The diagnostic value of plasma phosphorylated tau 181 in Alzheimer's disease within the Chinese population: A systematic review and meta-analysis

Journal of Alzheimer's Disease Reports
Background Among all related biomarkers, plasma phosphorylated tau (p-tau181) has demonstrated strong diagnostic performance in the very early stages of Alzheimer's disease (AD), showing significant differences between AD patients and healthy controls ...
Keqiang Yan, Haiyan Li, Shuxin He, Xiaodong Jia, Dequan Liu, Jianchun Chen   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Important multi-omics pathways identified by PathIntegrate Multi-View on COPDgene multi-omics data. [PDF]

Important multi-omics pathways identified by PathIntegrate Multi-View on COPDgene multi-omics data.
Cecilia Wieder (11402540), Juliette Cooke (11402543), Timothy Ebbels (2247136), Russell Bowler (3471647), Fabien Jourdan (216798), Rachel PJ Lai (8281866), Clement Frainay (18251699), Nathalie Poupin (195134), Katerina J. Kechris (9921356)   +8 more
core   +1 more source

Graph Contrastive Learning for Multi-omics Data [PDF]

, 2023
Advancements in technologies related to working with omics data require novel computation methods to fully leverage information and help develop a better understanding of human diseases.
Rajadhyaksha, Nishant, Chitkara, Aarushi
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Genetic structure analysis of a Northwest Chinese population using a self-developed DIP system and machine learning for forensic ancestry inference

BMC Genomics
This study investigates forensic ancestry inference in admixed populations using a self-developed 60-DIP panel, analyzing Kyrgyz samples from Northwest China (CNK) and 26 reference populations from the 1000 Genomes Project.
Meiming Cai, Ruonan Shen, Xin Shi, Yiman Wu, Lisiteng Luo, Qinglin Liang, Bofeng Zhu   +6 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Plant-pathogen interactions:Making the case for multi-omics analysis of complex pathosystems [PDF]

Understanding plant-pathogen interactions requires a systems-level perspective that single-omics approaches, such as genomics, transcriptomics, proteomics, or metabolomics alone, often fail to provide.
Balotf, Sadegh, Wilson, Richard, Mur, Luis A. J.; id_orcid, Mur, Luis A. J., Hemmati, Roghayeh, Eshaghi, Mahsa, Wilson, Calum   +6 more
core   +1 more source

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

Advanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco, Roberto Baretta, Andrea Di Fonzo, Andrea Armirotti, Stefano Cinti, Mara Mirasoli, Marco Frasconi, Claudia Corbo   +7 more
wiley   +1 more source

Visual analysis of multi-omics data

Frontiers in Bioinformatics
We present a tool for multi-omics data analysis that enables simultaneous visualization of up to four types of omics data on organism-scale metabolic network diagrams. The tool’s interactive web-based metabolic charts depict the metabolic reactions, pathways, and metabolites of a single organism as described in a metabolic pathway database for that ...
Austin Swart, Ron Caspi, Suzanne Paley, Peter D. Karp   +3 more
openaire   +3 more sources