Results 81 to 90 of about 79,155 (276)

PathIntegrate: Multivariate modelling approaches for pathway-based multi-omics data integration.

PLoS Computational Biology
As terabytes of multi-omics data are being generated, there is an ever-increasing need for methods facilitating the integration and interpretation of such data.
Cecilia Wieder, Juliette Cooke, Clement Frainay, Nathalie Poupin, Russell Bowler, Fabien Jourdan, Katerina J Kechris, Rachel Pj Lai, Timothy Ebbels   +8 more
doaj   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Multi-omics strategies for biomarker discovery and application in personalized oncology

Molecular Biomedicine
Multi-omics strategies, integrating genomics, transcriptomics, proteomics, and metabolomics, have revolutionized biomarker discovery and enabled novel applications in personalized oncology.
Ziming Jiang, Haoxuan Zhang, Yibo Gao, Yingli Sun   +3 more
doaj   +1 more source

Laser‐Microscribed Glass Enables Surface‐Microfluidics‐Facilitated, Affordable, Rapid Cancer Diagnosis

Advanced Functional Materials, EarlyView.
A transparent, laser‐microscribed glass platform enables cancer diagnosis within 1 h—much faster than histology, which takes days, and free from the chemical or contrast risks of MRI or CT scans. The antibody‐functionalized rough glass surface captures viable cancer cells directly from suspension, allowing instant optical readout and offering a rapid ...
Anish Pal, Snehasis Mishra, Arani Mukhopadhyay, Ilias Papailias, Atique U. Ahmed, Constantine M. Megaridis   +5 more
wiley   +1 more source

Omics-enhanced nanomedicine: integrating multi-omics for precision cancer diagnosis and therapy

Discover Oncology
Cancer nanomedicine has emerged as a transformative approach in oncology, providing targeted therapeutic strategies with enhanced efficacy and reduced systemic toxicity.
Lihui Yan, Boshi Duan, Tianyou Wang, Tianzuo Wang, Huanyu Chi, Hongji Gao   +5 more
doaj   +1 more source

Multi-omics decodes host-specific and environmental microbiome interactions in sepsis

Frontiers in Microbiology
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, and its pathogenesis involves complex interactions between the host and the microbiome.
Jiamin Lu, Jiamin Lu, Wen Zhang, Wen Zhang, Yuzhou He, Mei Jiang, Zhankui Liu, Jirong Zhang, Jirong Zhang, Lanzhi Zheng, Bingzhi Zhou, Jielian Luo, Jielian Luo, Chenming He, Chenming He, Yunan Shan, Runze Zhang, Runze Zhang, KaiLiang Fan, Bangjiang Fang, Bangjiang Fang, Chuanqi Wan, Chuanqi Wan   +22 more
doaj   +1 more source

Tricks to translating TB transcriptomics. [PDF]

, 2015
Transcriptomics and other high-throughput methods are increasingly applied to questions relating to tuberculosis (TB) pathogenesis. Whole blood transcriptomics has repeatedly been applied to define correlates of TB risk and has produced new insight into ...
Coussens, AK, Deffur, A, Wilkinson, RJ
core   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Artificial Intelligence-Driven Precision Medicine: Multi-Omics and Spatial Multi-Omics Approaches in Diffuse Large B-Cell Lymphoma (DLBCL)

Frontiers in Bioscience-Landmark
In this comprehensive review, we delve into the transformative role of artificial intelligence (AI) in refining the application of multi-omics and spatial multi-omics within the realm of diffuse large B-cell lymphoma (DLBCL) research.
Yanping Shao, Xiuyan Lv, Shuangwei Ying, Qunyi Guo   +3 more
doaj   +1 more source

Multi-omics Data Integration Model Based on UMAP Embedding and Convolutional Neural Network

Cancer Informatics, 2022
Introduction: Multi-omics data integration facilitates collecting richer understanding and perceptions than separate omics data. Various promising integrative approaches have been utilized to analyze multi-omics data for biomedical applications ...
Bashier ElKarami, Abedalrhman Alkhateeb, Hazem Qattous, Lujain Alshomali, Behnam Shahrrava   +4 more
doaj   +1 more source