Results 41 to 50 of about 15,176,596 (284)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Computing continuous-time growth models with boundary conditions via wavelets [PDF]

open access: yes, 2004
This paper presents an algorithm for approximating the solution of deterministic/stochastic continuous-time growth models based on the Euler's equation and the transversality conditions.
Vidal-Sanz, José M.   +1 more
core   +1 more source

On a system of higher-order multi-point boundary value problems

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
We investigate the existence and nonexistence of positive solutions for a system of nonlinear higher-order ordinary differential equations subject to some multi-point boundary conditions.
Johnny Henderson, Rodica Luca
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Positive solutions for a system of second-order discrete boundary value problems

open access: yesAdvances in Difference Equations, 2018
We study the existence and multiplicity of positive solutions for a system of nonlinear second-order difference equations subject to multi-point boundary conditions, under some assumptions on the nonlinearities of the system which contains concave ...
Ravi P. Agarwal, Rodica Luca
doaj   +1 more source

Coupled Systems of Nonlinear Integer and Fractional Differential Equations with Multi-Point and Multi-Strip Boundary Conditions

open access: yesMathematics, 2020
We first consider a second order coupled differential system with nonlinearities involved two unknown functions and their derivatives, subject to a new kinds of multi-point and multi-strip boundary value conditions.
Bin Di, Guo Chen, Huihui Pang
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Existence of three solutions for a higher-order boundary-value problem

open access: yesElectronic Journal of Differential Equations, 2009
We consider a higher-order multi-point boundary-value problem with a nonlinear boundary condition. Sufficient conditions are obtained for the existence of three solutions.
John R. Graef, Lingju Kong, Qingkai Kong
doaj  

Existence of three solutions for sytems of multi-point boundary value problems

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2009
By using a variational approach, we obtain some sufficient conditions for the existence of three classical solutions of a boundary value problem consisting of a system of differential equations and some multi-point boundary conditions.
Zengji Du, Lingju Kong
doaj   +1 more source

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