Results 61 to 70 of about 92,639 (261)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Solutions to second order non-homogeneous multi-point BVPs using a fixed-point theorem

Electronic Journal of Differential Equations, 2008
In this article, we study five non-homogeneous multi-point boundary-value problems (BVPs) of second order differential equations with the one-dimensional p-Laplacian.
Yuji Liu
doaj  

Existence and stability of solutions for a nonlocal multi-point and multi-strip coupled boundary value problem of nonlinear fractional Langevin equations

Bulletin of Mathematical Sciences
In this paper, we investigate a nonlocal multi-point and multi-strip coupled boundary value problem of nonlinear fractional Langevin equations. The standard fixed point theorems (Leray–Schauder’s alternative and Banach’s fixed point theorem) are applied ...
Ahmed Alsaedi, Hafed A. Saeed, Hamed Alsulami   +2 more
doaj   +1 more source

Positive solutions for singular systems of higher-order multi-point boundary value problems

Mathematical Modelling and Analysis, 2013
We investigate the existence of positive solutions for systems of singular nonlinear higher-order differential equations subject to multi-point boundary conditions.
Johnny Henderson, Rodica Luca
doaj   +1 more source

Nonlocal boundary value problems for Hilfer-type pantograph fractional differential equations and inclusions

Advances in Difference Equations, 2020
In this paper, we study boundary value problems, involving the Hilfer fractional derivative, for pantograph fractional differential equations and inclusions supplemented by nonlocal integral boundary conditions.
Athasit Wongcharoen, Sotiris K. Ntouyas, Jessada Tariboon   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Non-homogeneous boundary-value problems of higher order differential equations with p-Laplacian

Electronic Journal of Differential Equations, 2008
We establish sufficient conditions for the existence of positive solutions to five multi-point boundary value problems. These problems have a common equation (in different function domains) and different boundary conditions.
Yuji Liu
doaj  

Existence Analysis of Multi-Point Boundary Value Problems with Riesz-Caputo Fractional Derivatives [PDF]

Sahand Communications in Mathematical Analysis
This paper explores the study of a specific category of nonlinear multi-point boundary value problems (BVPs) associated with Riesz-Caputo fractional differential equations and integral boundary conditions.
Takieddine Zeghida, Rabah Khaldi, Assia Guezane-Lakoud   +2 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source