Results 51 to 60 of about 992,003 (291)

Calculable Sparticle Masses with Radiatively Driven Inverted Mass Hierarchy [PDF]

, 1999
Supersymmetric models with an inverted mass hierarchy (IMH: multi-TeV first and second generation matter scalars, and sub-TeV third generation scalars) can ameliorate problems arising from flavor changing neutral currents, $CP$ violating phases and ...
Dimopoulos, Dine, Fukuda, Gabbiani, Goto, Howard Baer, Nir, Pedro Mercadante, Xerxes Tata   +8 more
core   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Existence of three solutions for sytems of multi-point boundary value problems

Electronic Journal of Qualitative Theory of Differential Equations, 2009
By using a variational approach, we obtain some sufficient conditions for the existence of three classical solutions of a boundary value problem consisting of a system of differential equations and some multi-point boundary conditions.
Zengji Du, Lingju Kong
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Differential equations for multi-loop integrals and two-dimensional kinematics

, 2012
In this paper we consider multi-loop integrals appearing in MHV scattering amplitudes of planar N=4 SYM. Through particular differential operators which reduce the loop order by one, we present explicit equations for the two-loop eight-point finite ...
A Brandhuber, A Brandhuber, A Sever, AB Goncharov, C Duhr, D Gaiotto, D Gaiotto, E Remiddi, G Korchemsky, G Korchemsky, J Drummond, J Drummond, J Drummond, J Drummond, J Drummond, J Drummond, J Drummond, J Drummond, JM Drummond, JM Drummond, JM Drummond, L Mason, L. Ferro, LF Alday, LF Alday, LF Alday, LF Alday, LF Alday, LF Alday, LJ Dixon, LJ Dixon, LJ Dixon, MF Paulos, N Arkani-Hamed, N Arkani-Hamed, N Arkani-Hamed, P Heslop, P Heslop, S Caron-Huot, S Caron-Huot, T Gehrmann, V Duca Del, V Duca Del, V Duca Del, V Duca Del, Z Bern   +45 more
core   +1 more source

Linear, second-order problems with Sturm-Liouville-type multi-point boundary conditions

Electronic Journal of Differential Equations, 2011
We consider the linear eigenvalue problem \tag{1} -u" = u, \quad \text{on $(-1,1)$}, where $ \in \mathbb{R}$, together with the general multi-point boundary conditions \tag{2} _0^\pm u(\pm 1) + _0^\pm u'(\pm 1) = \sum^{m^\pm}_{i=1} ^\pm_i u( ^\pm_i) + \sum_{i=1}^{m^\pm} ^\pm_i u'( ^\pm_i).
openaire   +4 more sources

Positive solutions of second order multi-point boundary value problems with non-homogeneous boundary conditions [PDF]

Differential Equations & Applications, 2010
We are interested in the existence of positive solutions to multi-point boundary value problems for second order nonlinear differential equations with non-homogeneous boundary conditions. We show that results for the multi-point problems can be proved much in a similar way by methods available for the three point problem.
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Existence of positive solutions for a semipositone discrete boundary value problem

Nonlinear Analysis, 2019
We investigate the existence of positive solutions for a nonlinear second-order difference equation with a linear term and a sign-changing nonlinearity, supplemented with multi-point boundary conditions.
Rodica Luca
doaj   +1 more source

Review of Summation-by-parts schemes for initial-boundary-value problems

, 2013
High-order finite difference methods are efficient, easy to program, scales well in multiple dimensions and can be modified locally for various reasons (such as shock treatment for example).
Nordström, Jan, Svärd, Magnus
core   +1 more source