Results 51 to 60 of about 92,639 (261)

Fractional Differential Equation Involving Mixed Nonlinearities with Nonlocal Multi-Point and Riemann-Stieltjes Integral-Multi-Strip Conditions

Fractal and Fractional, 2019
In this paper, we investigate a new class of boundary value problems involving fractional differential equations with mixed nonlinearities, and nonlocal multi-point and Riemann−Stieltjes integral-multi-strip boundary conditions.
Bashir Ahmad, Ahmed Alsaedi, Sara Salem, Sotiris K. Ntouyas   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Some results on impulsive boundary value problem for fractional differential inclusions

Electronic Journal of Qualitative Theory of Differential Equations, 2011
This paper deals with impulsive fractional differential inclusions with a fractional order multi-point boundary condition and with fractional order impulses.
Jianxin Cao, Haibo Chen
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Linear second-order problems with Sturm-Liouville-type multi-point boundary conditions

Electronic Journal of Differential Equations, 2012
We consider the eigenvalue problem for the equation $-u'' = lambda u$ on $(-1,1)$, together with general Sturm-Liouville-type, multi-point boundary conditions at $pm 1$. We show that the basic spectral properties of this problem are similar to those
Bryan P. Rynne
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Positive nondecreasing solutions for a multi-term fractional-order functional differential equation with integral conditions

Electronic Journal of Differential Equations, 2011
In this article, we prove the existence of positive nondecreasing solutions for a multi-term fractional-order functional differential equations. We consider Cauchy boundary problems with: nonlocal conditions, two-point boundary conditions, integral ...
Ahmed M. A. El-Sayed, Ebtisam O. Bin-Taher   +1 more
doaj  

On Caputo–Riemann–Liouville Type Fractional Integro-Differential Equations with Multi-Point Sub-Strip Boundary Conditions

Mathematics, 2020
In this paper, we derive existence and uniqueness results for a nonlinear Caputo–Riemann–Liouville type fractional integro-differential boundary value problem with multi-point sub-strip boundary conditions, via Banach and Krasnosel’skii⏝’s fixed point ...
Ahmed Alsaedi, Amjad F. Albideewi, Sotiris K. Ntouyas, Bashir Ahmad   +3 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source