Results 61 to 70 of about 1,245,641 (265)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Teleoperated Magnetic Endoscopy: A Case Study and Perspective
Teleoperated robotic surgery is a rapidly growing field that promises to overcome geographical barriers and share expertise over long distances for a variety of minimally invasive procedures.
Alexandre Mesot +8 more
doaj +1 more source
Multi-scale time-stepping in molecular dynamics
We introduce a modified molecular dynamics algorithm that allows one to freeze the dynamics of parts of a physical system, and thus concentrate the simulation effort on selected, central degrees of freedom. This freezing, in contrast to other multi-scale
Maggs, A. C.
core +3 more sources
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Ultrasound-mediated piezoelectric differentiation of neuron-like PC12 cells on PVDF membranes
Electrical and/or electromechanical stimulation has been shown to play a significant role in regenerating various functionalities in soft tissues, such as tendons, muscles, and nerves. In this work, we investigate the piezoelectric polymer polyvinylidene
Marcus Hoop +8 more
doaj +1 more source
Multi-Scale CLEAN deconvolution of radio synthesis images
Radio synthesis imaging is dependent upon deconvolution algorithms to counteract the sparse sampling of the Fourier plane. These deconvolution algorithms find an estimate of the true sky brightness from the necessarily incomplete sampled visibility data.
Cornwell, T. J.
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Ni(OH)2 has been extensively studied as a promising electrocatalyst for the oxygen evolution reaction (OER). However, enhancing its OER properties is still required and challenging.
Wei Cui +6 more
doaj +1 more source
A Terahertz Polarizer Based on Multilayer Metal Grating Filled in Polyimide Film
Terahertz (THz) polarizers with low reflection and absorption loss and high polarization extinction ratio (PER) based on multilayer metallic gratings filled in a polyimide film were studied theoretically and experimentally.
Hong-Yan Mao +9 more
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source

