Results 91 to 100 of about 11,603,043 (210)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
AMHFN: Aggregation Multi-Hierarchical Feature Network for Hyperspectral Image Classification
Remote SensingDeep learning methods like convolution neural networks (CNNs) and transformers are successfully applied in hyperspectral image (HSI) classification due to their ability to extract local contextual features and explore global dependencies, respectively ...
Xiaofei Yang +5 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 2019 The high interior heterogeneity of land surface covers in high-resolution image of coastal cities makes classification challenging. To meet this challenge, a Multi-Scale Superpixels-based Classification method using Optimized Spectral−Spatial ...
Shuang Zhang +8 more
core +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
, 2008 International audienceMulti-scale features of turbulent flames near a wall display two kinds of scale-dependent fractal features. In scale-space, an unique fractal dimension cannot be defined and the fractal dimension of the front is scale-dependent ...
Kassema, H. +4 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Multi-scale visual attention and saliency modelling with decision theory
, 2013 Recently, an information-based saliency technique which is biologically plausible and computationally feasible called Discriminant Saliency (DIS) has been proposed.
AC Le Ngo (15859514) +3 more
core
Multi-Scale Salient Features for Analyzing 3D Shapes [PDF]
, 2012 Extracting feature regions on mesh models is crucial for shape analysis and understanding. It can be widely used for various 3D content-based applications in graphics and geometry field. In this paper, we present a new algorithm of extracting multi-scale
Chao-hui Shen (沈超慧 +1 more
core