Results 81 to 90 of about 11,603,043 (210)

Multi-Scale Self-Attention for Text Classification

, 2020
In this paper, we introduce the prior knowledge, multi-scale structure, into self-attention modules. We propose a Multi-Scale Transformer which uses multi-scale multi-head self-attention to capture features from different scales.
Guo, Qipeng, Zhang, Zheng, Qiu, Xipeng, Xue, Xiangyang, Liu, Pengfei   +4 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Optimized DINO model for accurate object detection of sesame seedlings and weeds

Scientific Reports
The application of intelligent agricultural machinery is crucial in modern agricultural production. However, in environments where the target and the surrounding morphology are highly similar, such as distinguishing sesame seedlings from weeds, the ...
Yong Wang, ShunFa Xu, ZhenYuan Ye, KongHao Cheng   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

An Efficient Group Convolution and Feature Fusion Method for Weed Detection

Agriculture
Weed detection is a crucial step in achieving intelligent weeding for vegetables. Currently, research on vegetable weed detection technology is relatively limited, and existing detection methods still face challenges due to complex natural conditions ...
Chaowen Chen, Ying Zang, Jinkang Jiao, Daoqing Yan, Zhuorong Fan, Zijian Cui, Minghua Zhang   +6 more
doaj   +1 more source

A Note on Equivalences in Measuring Returns to Scale in Multi-output-multi-input Technologies [PDF]

In this article we show equivalence between the input oriented and output oriented scale elasticity measures for multi-output, multi-input technologies. We show the necessary and sufficient condition for this equivalence.
Valentin Zelenyuk
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Crack-MsCGA: A Deep Learning Network with Multi-Scale Attention for Pavement Crack Detection

Sensors
Pavement crack detection is crucial for ensuring road safety and reducing maintenance costs. Existing methods typically use convolutional neural networks (CNNs) to extract multi-level features from pavement images and employ attention mechanisms to ...
Guoxi Liu, Xiaojing Wu, Fei Dai, Guozhi Liu, Lecheng Li, Bi Huang   +5 more
doaj   +1 more source