Results 71 to 80 of about 494,722 (259)

From Kernels to Features: A Multi-Scale Adaptive Theory of Feature Learning

CoRR
Feature learning in neural networks is crucial for their expressive power and inductive biases, motivating various theoretical approaches. Some approaches describe network behavior after training through a change in kernel scale from initialization, resulting in a generalization power comparable to a Gaussian process.
Noa Rubin, Kirsten Fischer, Javed Lindner, David Dahmen, Inbar Seroussi, Zohar Ringel, Michael Krämer, Moritz Helias   +7 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Multi-Scale Earthquake Damaged Building Feature Set

Data
Earthquake disasters are marked by their unpredictability and potential for extreme destructiveness. Accurate information on building damage, captured in post-earthquake remote sensing images, is critical for an effective post-disaster emergency response.
Guorui Gao, Futao Wang, Zhenqing Wang, Qing Zhao, Litao Wang, Jinfeng Zhu, Wenliang Liu, Gang Qin, Yanfang Hou   +8 more
openaire   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

VarKFaceNet: An Efficient Variable Depthwise Convolution Kernels Neural Network for Lightweight Face Recognition

IEEE Access
We revisit the design of convolutional kernels in lightweight convolutional neural networks, and inspired by the recent advances in RepLKNet, we design a Variable Kernel Convolutional Network module VarKNet, which solves the problem of the imbalance ...
Qinghua Ma, Peng Zhang, Min Cui
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

An Efficient Group Convolution and Feature Fusion Method for Weed Detection

Agriculture
Weed detection is a crucial step in achieving intelligent weeding for vegetables. Currently, research on vegetable weed detection technology is relatively limited, and existing detection methods still face challenges due to complex natural conditions ...
Chaowen Chen, Ying Zang, Jinkang Jiao, Daoqing Yan, Zhuorong Fan, Zijian Cui, Minghua Zhang   +6 more
doaj   +1 more source

Multi‐Scale Feature Guided Transformer for Image Inpainting

IET Image Processing
ABSTRACT In recent years, image restoration has witnessed remarkable advancements. However, reconstructing visually plausible textures while preserving global structural coherence remains a persistent challenge. Existing convolutional neural network (CNN)‐based approaches are inherently limited by their local receptive fields, often ...
Zeji Huang, Huanda Lu, Xin Yu, Hui Xiao
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source