Results 121 to 130 of about 20,830,634 (309)

Multi-Scale Integrated Analysis of Societal and Ecosystem Metabolism (MUSIASEM): An Outline of Rationale and Theory [PDF]

open access: yes
This paper presents an outline of rationale and theory of the MuSIASEM scheme (Multi-Scale Integrated Analysis of Societal and Ecosystem Metabolism).
Kozo Mayumi   +2 more
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Multi-Scale Generative Modeling for Fast Sampling

open access: yesICASSP 2026 - 2026 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)
While working within the spatial domain can pose problems associated with ill-conditioned scores caused by power-law decay, recent advances in diffusion-based generative models have shown that transitioning to the wavelet domain offers a promising alternative.
Xiongye Xiao   +8 more
openaire   +2 more sources

Application Integration Control System for Multi-Scale and Multi-PhysicsSimulation [PDF]

open access: yes, 2010
In the case of long-period and large-scale simulation, unexpected stop which is caused by execution time excess, outage of computers, outage of a network during file transfer and so on, become major issues.
SUZUKI, Yoshio   +7 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Multi-scale 3-D Surface Description: Open and Closed Surfaces [PDF]

open access: yes, 1999
A novel technique for multi-scale smoothing of a free-form 3-D surface is presented. Complete triangulated models of 3-D objects are constructed automatically and using a local parametrization technique, are then smoothed using a 2-D Gaussian filter. Our
Yuen, P   +5 more
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Multi-scale and Multimodal Species Distribution Modeling

open access: yes
Published at the CV4Ecology workshop at ECCV 2024 (https://cv4e.netlify.app/papers/06.pdf)
Nina Van Tiel   +5 more
openaire   +4 more sources

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