Results 111 to 120 of about 20,830,634 (309)

EPOS Multi-scale laboratories Data Services & Trans-national access program

open access: yes, 2020
EGU2020: Sharing Geoscience Online, 4-8 May, 2020EPOS (European Plate Observing System) is an ESFRI Landmark and European Research Infrastructure Consortium (ERIC).
Fernandez-Turiel, J. L.   +3 more
core   +1 more source

MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]

open access: yes, 2012
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
Kierzek, A.M.   +42 more
core   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Paris on Stage: 1889-1914 [exhibition]; Vespasienne (pissoir) Model

open access: yes, 2013
Information label with photograph of original, in situ; Scale model, part of the Paris on Stage: 1889-1914 exhibition held June 19, 2013 to February 23, 2014.
unknown (Canadian model maker)
core  

Advances and visions in large-scale hydrological modelling : findings from the 11th Workshop on Large-Scale Hydrological Modelling [PDF]

open access: yes, 2008
Large-scale hydrological modelling has become increasingly wide-spread during the last decade. An annual workshop series on large-scale hydrological modelling has provided, since 1997, a forum to the German-speaking community for discussing recent ...
K. Berkhoff   +21 more
core   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Multi-scale coupling mechanisms and dynamic evolution: a review of theoretical research on freeze-thaw resistance of recycled aggregate concrete

open access: yesReviews on Advanced Materials Science
The poor freeze-thaw (F-T) durability of recycled aggregate concrete (RAC) limits its cold-region application. This review systematically elucidates the multi-scale deterioration mechanisms of RAC under F-T action.
Xuan Wei   +6 more
doaj   +1 more source

Multi-Scale Model for the Aging Performance of Particle-Filled Polymer Composites. [PDF]

open access: yesPolymers (Basel), 2023
Fang C   +5 more
europepmc   +1 more source

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