Results 101 to 110 of about 20,830,634 (309)

Left Lung Model featuring Upper and Lower Lobes

open access: yes, 2020
This is a multi-colored left lung model where each color designates a specific segment of the upper and lower lobes.

core  

neworderofjamie/multi-area-model: PyGeNN multiarea model 1.0.0

open access: yes, 2020
Version of multi-area model to accompany "Larger GPU-accelerated brain simulations with procedural ...
Jari Pronold   +4 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Right Lung Model featuring Upper, Middle and Lower Lobes

open access: yes, 2020
This is a multi-colored right lung model where each color designates a segment of the upper, middle, and lower lobes.

core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Multi-Scale Free-Form Surface Description and Curvature Estimation [PDF]

open access: yes, 1999
A novel technique for multi-scale smoothing of a free-form 3-D surface is presented. Complete triangulated models of 3-D objects are constructed at our center [4] and using a local parametrization technique, are then smoothed using a 2-D Gaussian filter.
Yuen, P, Mokhtarian, F, Khalili, N
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

A Multi-Scale–Multi-Stable Model for the Rhodopsin Photocycle

open access: yesMolecules, 2014
We report a multi-scale simulation study of the photocycle of the rhodopsins. The quasi-atomistic representation (“united atoms” UA) of retinal is combined with a minimalist coarse grained (CG, one-bead-per amino acid) representation of the protein, in a
Francesco Tavanti, Valentina Tozzini
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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