Results 81 to 90 of about 20,830,634 (309)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Multi-scale Multi-step ontology
, 2015 The Multi-scale Multi-step ontology (MS²O) is an ontology to describe transformation processes. IMPORTANT : MS²O is obsolete.
Dervaux, Stéphane, Dibie, Juliette
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Cerebrovascular Smooth Muscle Cells as the Drivers of Intramural Periarterial Drainage of the Brain
Frontiers in Aging Neuroscience, 2019 The human brain is the organ with the highest metabolic activity but it lacks a traditional lymphatic system responsible for clearing waste products.
Roxana Aldea +4 more
doaj +1 more source
Object detection model of coal mine rescue robot based on multi -scale feature fusio
Gong-kuang zidonghua, 2020 Traditional object detection model uses artificial object features, resulting in poor detection accuracy. Object detection model based on deep learning has high detection accuracy.
ZHAI Guodong +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Multi-scale computational modeling of developmental biology [PDF]
Bioinformatics, 2012 Abstract Motivation: Normal development of multicellular organisms is regulated by a highly complex process in which a set of precursor cells proliferate, differentiate and move, forming over time a functioning tissue. To handle their complexity, developmental systems can be studied over distinct scales.
openaire +3 more sources
Multi-scale modeling of dense gas-particle flows
, 2012 Dense gas-particle flows are encountered in a variety of industrially important processes for large scale production of fuels, fertilizers and base chemicals.
Kuipers, J.A.M.; id_orcid +2 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Automated Extraction Of Small Structures In Medical Images Based On Multi Scale Approach. [PDF]
, 2004 Multi scale techniques coupled with active contours have been widely used to locate the boundaries of structures in noisy images.
Ramachandram, Dhanesh +2 more
core +1 more source